Kening Jiang1, Adam P Spira2,3, Nicholas S Reed1,4, Frank R Lin1,5, Jennifer A Deal1,4. 1. Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. 2. Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. 3. Johns Hopkins Center on Aging and Health, Baltimore, Maryland, USA. 4. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. 5. Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Abstract
BACKGROUND: Sleep characteristics might be associated with hearing loss through disturbed energy metabolism and disrupted cochlear blood flow, but prior evidence is limited. This study aims to investigate cross-sectional associations of sleep duration and signs/symptoms of sleep-disordered breathing with hearing in a nationally representative cohort of US older adults aged 70 and older. METHODS: We studied 632 older adults aged 70 and older from the 2005-2006 cycle of the National Health and Nutrition Examination Survey. Hearing thresholds were measured using pure-tone audiometry and were averaged to create speech-frequency (0.5-4 kHz), low-frequency (0.5-2 kHz), and high-frequency (4-8 kHz) pure-tone averages (PTAs) in better-hearing ear, with higher values indicate worse hearing. Sleep duration and signs/symptoms of sleep-disordered breathing (snoring, snorting/stopping breathing, excessive sleepiness) were collected through questionnaires. Multivariable-adjusted spline models with knots at 6 and 8 hours were fitted for associations between sleep duration and PTAs. Multivariable-adjusted linear regression was used for associations between sleep-disordered breathing and PTAs. Primary models adjusted for demographic and lifestyle factors, secondary models additionally adjusted for cardiovascular factors. RESULTS: When sleep duration exceeded 8 hours, every additional hour of sleep duration was marginally associated with higher(poorer) high-frequency PTA (primary: 2.45 dB in hearing level, 95% CI: -0.34 to 5.24; secondary: 2.89 dB in hearing level, 95% CI: 0.02-5.76). No associations were observed between sleep-disordered breathing and hearing. CONCLUSIONS: Longer sleep duration is marginally associated with poorer high-frequency hearing among older adults sleeping more than 8 hours. However, we cannot infer temporality given the cross-sectional design. Future longitudinal studies are needed to establish temporality and clarify mechanisms.
BACKGROUND: Sleep characteristics might be associated with hearing loss through disturbed energy metabolism and disrupted cochlear blood flow, but prior evidence is limited. This study aims to investigate cross-sectional associations of sleep duration and signs/symptoms of sleep-disordered breathing with hearing in a nationally representative cohort of US older adults aged 70 and older. METHODS: We studied 632 older adults aged 70 and older from the 2005-2006 cycle of the National Health and Nutrition Examination Survey. Hearing thresholds were measured using pure-tone audiometry and were averaged to create speech-frequency (0.5-4 kHz), low-frequency (0.5-2 kHz), and high-frequency (4-8 kHz) pure-tone averages (PTAs) in better-hearing ear, with higher values indicate worse hearing. Sleep duration and signs/symptoms of sleep-disordered breathing (snoring, snorting/stopping breathing, excessive sleepiness) were collected through questionnaires. Multivariable-adjusted spline models with knots at 6 and 8 hours were fitted for associations between sleep duration and PTAs. Multivariable-adjusted linear regression was used for associations between sleep-disordered breathing and PTAs. Primary models adjusted for demographic and lifestyle factors, secondary models additionally adjusted for cardiovascular factors. RESULTS: When sleep duration exceeded 8 hours, every additional hour of sleep duration was marginally associated with higher(poorer) high-frequency PTA (primary: 2.45 dB in hearing level, 95% CI: -0.34 to 5.24; secondary: 2.89 dB in hearing level, 95% CI: 0.02-5.76). No associations were observed between sleep-disordered breathing and hearing. CONCLUSIONS: Longer sleep duration is marginally associated with poorer high-frequency hearing among older adults sleeping more than 8 hours. However, we cannot infer temporality given the cross-sectional design. Future longitudinal studies are needed to establish temporality and clarify mechanisms.
Authors: Erika Matsumura; Carla G Matas; Seisse G G Sanches; Fernanda C L Magliaro; Raquel M Pedreño; Pedro R Genta; Geraldo Lorenzi-Filho; Renata M M Carvallo Journal: Sleep Breath Date: 2017-07-05 Impact factor: 2.816
Authors: Karen J Cruickshanks; David M Nondahl; Dayna S Dalton; Mary E Fischer; Barbara E K Klein; Ronald Klein; F Javier Nieto; Carla R Schubert; Ted S Tweed Journal: J Am Geriatr Soc Date: 2015-05-06 Impact factor: 5.562
Authors: Pablo Martinez-Amezcua; Danielle Powell; Pei-Lun Kuo; Nicholas S Reed; Kevin J Sullivan; Priya Palta; Moyses Szklo; Richey Sharrett; Jennifer A Schrack; Frank R Lin; Jennifer A Deal Journal: JAMA Netw Open Date: 2021-06-01