Literature DB >> 3430163

Hepatoprotective activity of polyphenolic compounds from Cynara scolymus against CCl4 toxicity in isolated rat hepatocytes.

T Adzet1, J Camarasa, J C Laguna.   

Abstract

The hepatoprotective activity against CCl4 toxicity in isolated rat hepatocytes of some polyphenolic compounds, such as cynarin, isochlorogenic acid, chlorogenic acid, luteolin-7-glucoside, and two organic acids, caffeic and quinic, from Cynara scolymus, is tested. Only cynarine and, to a lesser extent, caffeic acid showed cytoprotective action. The possible relationship between the molecular structure and the protective effect found is discussed.

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Year:  1987        PMID: 3430163     DOI: 10.1021/np50052a004

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  17 in total

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2.  Eleusine indica L. possesses antioxidant activity and precludes carbon tetrachloride (CCl₄)-mediated oxidative hepatic damage in rats.

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4.  Isolation and mapping of a C3'H gene (CYP98A49) from globe artichoke, and its expression upon UV-C stress.

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6.  Gene expression profiling reveals underlying molecular mechanism of hepatoprotective effect of Phyllanthus niruri on thioacetamide-induced hepatotoxicity in Sprague Dawley rats.

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Journal:  BMC Complement Altern Med       Date:  2013-07-05       Impact factor: 3.659

7.  Effects of artichoke (Cynara scolymus) leaf and bloom head extracts on chemically induced DNA lesions in Drosophila melanogaster.

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Journal:  Genet Mol Biol       Date:  2013-02-28       Impact factor: 1.771

8.  Genome-Wide Identification of BAHD Acyltransferases and In vivo Characterization of HQT-like Enzymes Involved in Caffeoylquinic Acid Synthesis in Globe Artichoke.

Authors:  Andrea Moglia; Alberto Acquadro; Kaouthar Eljounaidi; Anna M Milani; Cecilia Cagliero; Patrizia Rubiolo; Andrea Genre; Katarina Cankar; Jules Beekwilder; Cinzia Comino
Journal:  Front Plant Sci       Date:  2016-09-23       Impact factor: 5.753

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Authors:  Isaac Julius Asiedu-Gyekye; Kennedy Kwami Edem Kukuia; Abdulai Mahmood Seidu; Charles Antwi-Boasiako; Benoit Banga N'guessan; Samuel Frimpong-Manso; Samuel Adjei; Jonathan Zobi; Abraham Terkpertey Tettey; Alexander Kwadwo Nyarko
Journal:  Evid Based Complement Alternat Med       Date:  2016-07-14       Impact factor: 2.629

10.  Dig1 protects against locomotor and biochemical dysfunctions provoked by Roundup.

Authors:  Steeve Gress; Claire Laurant; Nicolas Defarge; Carine Travert; Gilles-Éric Séralini
Journal:  BMC Complement Altern Med       Date:  2016-07-22       Impact factor: 3.659

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