Literature DB >> 3429840

Chronic active hepatitis caused by benzarone.

G Babany1, D Larrey, D Pessayre, C Degott, B Rueff, J P Benhamou.   

Abstract

We report a case of chronic active hepatitis caused by benzarone, a benzofuran derivative used in Europe for the treatment of peripheral venous disorders. Jaundice and serum alanine aminotransferase activity increased while drug administration was continued, but promptly decreased when it was eventually interrupted. Liver lesions were those of chronic active hepatitis. Anti-smooth muscle antibodies were present at a titer of 1:500 and disappeared 8 months after withdrawal of benzarone.

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Year:  1987        PMID: 3429840     DOI: 10.1016/s0168-8278(87)80039-9

Source DB:  PubMed          Journal:  J Hepatol        ISSN: 0168-8278            Impact factor:   25.083


  6 in total

1.  Autoimmune hepatitis and thyroiditis associated with rifampin and pyrazinamide prophylaxis: an unusual reaction.

Authors:  Omar Khokhar; Christopher Gange; Stephen Clement; James Lewis
Journal:  Dig Dis Sci       Date:  2005-01       Impact factor: 3.199

2.  [Drug Treatment of Chronic Venous Diesease].

Authors:  Miloš D Pavlović
Journal:  Wien Med Wochenschr       Date:  2016-07-05

Review 3.  Drug-induced "allergic hepatitis".

Authors:  P Podevin; M Biour
Journal:  Clin Rev Allergy Immunol       Date:  1995       Impact factor: 8.667

4.  Autoimmune hepatitis following drug-induced liver injury in an elderly patient.

Authors:  Junichiro Kumagai; Tatsuo Kanda; Shin Yasui; Yuki Haga; Reina Sasaki; Masato Nakamura; Shuang Wu; Shingo Nakamoto; Makoto Arai; Yotaro Iino; Osamu Yokosuka
Journal:  Clin J Gastroenterol       Date:  2016-05-12

5.  Emerging club drugs: 5-(2-aminopropyl)benzofuran (5-APB) is more toxic than its isomer 6-(2-aminopropyl)benzofuran (6-APB) in hepatocyte cellular models.

Authors:  Rita Roque Bravo; Helena Carmo; João Pedro Silva; Maria João Valente; Félix Carvalho; Maria de Lourdes Bastos; Diana Dias da Silva
Journal:  Arch Toxicol       Date:  2019-12-14       Impact factor: 5.153

Review 6.  Drug-induced autoimmune-like hepatitis.

Authors:  Albert J Czaja
Journal:  Dig Dis Sci       Date:  2011-02-16       Impact factor: 3.487

  6 in total

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