Literature DB >> 34295082

Is Roux Loop a Solution to Delayed Gastric Emptying Following Pancreaticoduodenectomy? A Single Institute Analysis.

B R Keerthi1, G N Hemanth1, M S Ganesh1, Amritha Prabha1, I Abhinay1.   

Abstract

Delayed gastric emptying is one of the most common complications of pancreaticoduodenectomy (PD). It almost always results in delayed oral intake, prolonged hospital stays, and a delay in initiation of vital adjuvant treatment. A few earlier studies suggested that delayed gastric emptying (DGE) rates were better with the Roux-en Y reconstruction, but Indian literature regarding this is lacking. In our institutional study, we compared the traditional single-loop reconstruction (SL group), with the Roux loop reconstruction (RY group) following a subtotal stomach-preserving pancreaticoduodenectomy (SSPPD). A retrospective comparative study was conducted between the conventional single loop and a Roux-en-Y method of reconstruction following a subtotal stomach preserving pancreaticoduodenectomy (SSPPD). Sixty-three consecutive Whipple's procedures were analyzed for multiple clinical parameters like removal of Ryles tube, tolerance of liquid diet and solid diet, delayed gastric emptying, duration of hospital stay and interval between surgery, and initiation of adjuvant treatment. Forty-one patients in the SL group were compared with 22 patients in the RY group. Ryles tube removal (POD 8.2 versus 2.25, p < 0.001), initiation of liquid diet (POD 8.43 versus 2.88, p < 0.001), post-operative hospital stay (13.5 days versus 9.63, p < 0.001), and interval between surgery and adjuvant treatment (37.75 days versus 28.88 days, p < 0.002) were all in favor of the RY group. The delayed gastric emptying was also found to be significantly better in the Roux-en-Y surgery group (p < 0.001). The Roux loop reconstruction following a stomach-preserving pancreaticoduodenectomy (SSPPD) is superior to single-loop reconstruction with respect to delayed gastric emptying. The lesser duration of hospital stay and early initiation of adjuvant therapy are an additional benefit of the Roux loop reconstruction. © Indian Association of Surgical Oncology 2021.

Entities:  

Keywords:  Delayed gastric emptying (DGE); Pancreaticoduodenectomy; Roux-en-Y

Year:  2021        PMID: 34295082      PMCID: PMC8272770          DOI: 10.1007/s13193-021-01298-5

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  26 in total

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Journal:  Dig Surg       Date:  2001       Impact factor: 2.588

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Authors:  Moritz N Wente; Claudio Bassi; Christos Dervenis; Abe Fingerhut; Dirk J Gouma; Jakob R Izbicki; John P Neoptolemos; Robert T Padbury; Michael G Sarr; L William Traverso; Charles J Yeo; Markus W Büchler
Journal:  Surgery       Date:  2007-11       Impact factor: 3.982

Review 3.  The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After.

Authors:  Claudio Bassi; Giovanni Marchegiani; Christos Dervenis; Micheal Sarr; Mohammad Abu Hilal; Mustapha Adham; Peter Allen; Roland Andersson; Horacio J Asbun; Marc G Besselink; Kevin Conlon; Marco Del Chiaro; Massimo Falconi; Laureano Fernandez-Cruz; Carlos Fernandez-Del Castillo; Abe Fingerhut; Helmut Friess; Dirk J Gouma; Thilo Hackert; Jakob Izbicki; Keith D Lillemoe; John P Neoptolemos; Attila Olah; Richard Schulick; Shailesh V Shrikhande; Tadahiro Takada; Kyoichi Takaori; William Traverso; Charles R Vollmer; Christopher L Wolfgang; Charles J Yeo; Roberto Salvia; Marcus Buchler
Journal:  Surgery       Date:  2016-12-28       Impact factor: 3.982

4.  Effect of Billroth II or Roux-en-Y Reconstruction for the Gastrojejunostomy After Pancreaticoduodenectomy: Meta-analysis of Randomized Controlled Trials.

Authors:  Ji Yang; Chao Wang; Qiang Huang
Journal:  J Gastrointest Surg       Date:  2015-03-19       Impact factor: 3.452

Review 5.  Clinical risk factors of delayed gastric emptying in patients after pancreaticoduodenectomy: a systematic review and meta-analysis.

Authors:  H Qu; G R Sun; S Q Zhou; Q S He
Journal:  Eur J Surg Oncol       Date:  2013-01-05       Impact factor: 4.424

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Journal:  Am J Dig Dis       Date:  1977-02

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Authors:  D L Wingate
Journal:  Dig Dis Sci       Date:  1983-12       Impact factor: 3.199

8.  Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: a prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumors.

Authors:  Khe T C Tran; Hans G Smeenk; Casper H J van Eijck; Geert Kazemier; Wim C Hop; Jan Willem G Greve; Onno T Terpstra; Jan A Zijlstra; Piet Klinkert; Hans Jeekel
Journal:  Ann Surg       Date:  2004-11       Impact factor: 12.969

9.  Total duodenectomy: effect on canine gastrointestinal motility.

Authors:  M Tanaka; M G Sarr
Journal:  J Surg Res       Date:  1987-05       Impact factor: 2.192

10.  Proximal Roux-en-y Gastrojejunal Anastomosis with Pyloric Ring Resection Improves Gastric Emptying After Pancreaticoduodenectomy.

Authors:  Omar Barakat; Martha N Cagigas; Shima Bozorgui; Claire F Ozaki; R Patrick Wood
Journal:  J Gastrointest Surg       Date:  2016-02-05       Impact factor: 3.452

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