| Literature DB >> 34294993 |
Chung Hong Tan1, Saifuddin Nomanbhay1, Abd Halim Shamsuddin1, Pau Loke Show2.
Abstract
In our modern world, biotechnology products play important roles not only in our health and culture, but also various industries such as food, agriculture, sewage treatment, biofuels, nutraceuticals, and pharmaceuticals. Rapid technological advances in biotechnology over the last few decades have allowed industrial integration of mammalian cells (like the Chinese hamster ovary cells) and algae cells in pharmaceutical and biofuel industries to produce commercial products and valuable biomolecules. However, the cost of cell harvest and recovery can become expensive depending on the harvesting technique, degree of purification, and intended use of the end-products. This has led to numerous research in exploring and developing efficient harvesting techniques. Therefore, in this review, the popular harvesting techniques and their recent applications will be discussed. © Association of Microbiologists of India 2021.Entities:
Keywords: CHO; Centrifugation; Depth filtration; Harvest; Tangential flow filtration
Year: 2021 PMID: 34294993 PMCID: PMC8263815 DOI: 10.1007/s12088-021-00930-w
Source DB: PubMed Journal: Indian J Microbiol ISSN: 0046-8991