Literature DB >> 34294993

Recent Progress in Harvest and Recovery Techniques of Mammalian and Algae Cells for Industries.

Chung Hong Tan1, Saifuddin Nomanbhay1, Abd Halim Shamsuddin1, Pau Loke Show2.   

Abstract

In our modern world, biotechnology products play important roles not only in our health and culture, but also various industries such as food, agriculture, sewage treatment, biofuels, nutraceuticals, and pharmaceuticals. Rapid technological advances in biotechnology over the last few decades have allowed industrial integration of mammalian cells (like the Chinese hamster ovary cells) and algae cells in pharmaceutical and biofuel industries to produce commercial products and valuable biomolecules. However, the cost of cell harvest and recovery can become expensive depending on the harvesting technique, degree of purification, and intended use of the end-products. This has led to numerous research in exploring and developing efficient harvesting techniques. Therefore, in this review, the popular harvesting techniques and their recent applications will be discussed. © Association of Microbiologists of India 2021.

Entities:  

Keywords:  CHO; Centrifugation; Depth filtration; Harvest; Tangential flow filtration

Year:  2021        PMID: 34294993      PMCID: PMC8263815          DOI: 10.1007/s12088-021-00930-w

Source DB:  PubMed          Journal:  Indian J Microbiol        ISSN: 0046-8991


  9 in total

1.  Exploitation of the adsorptive properties of depth filters for host cell protein removal during monoclonal antibody purification.

Authors:  Yinges Yigzaw; Robert Piper; Minh Tran; Abhinav A Shukla
Journal:  Biotechnol Prog       Date:  2006 Jan-Feb

Review 2.  Advances in primary recovery: centrifugation and membrane technology.

Authors:  David J Roush; Yuefeng Lu
Journal:  Biotechnol Prog       Date:  2008-04-15

3.  Control of antibody high and low molecular weight species by depth filtration-based cell culture harvesting.

Authors:  Deqiang Yu; Mukesh Mayani; Yuanli Song; Zhizhuo Xing; Sanchayita Ghose; Zheng Jian Li
Journal:  Biotechnol Bioeng       Date:  2019-06-29       Impact factor: 4.530

4.  Shear contributions to cell culture performance and product recovery in ATF and TFF perfusion systems.

Authors:  Samantha Wang; Scott Godfrey; Janani Ravikrishnan; Henry Lin; Jens Vogel; Jon Coffman
Journal:  J Biotechnol       Date:  2017-01-31       Impact factor: 3.307

5.  Pretreatments for enhancing clarification efficiency of depth filtration during production of monoclonal antibody therapeutics.

Authors:  Sandeep R Hadpe; Vipin Mohite; Solomon Alva; Anurag S Rathore
Journal:  Biotechnol Prog       Date:  2020-04-13

Review 6.  Cell engineering and cultivation of chinese hamster ovary (CHO) cells.

Authors:  Takeshi Omasa; Masayoshi Onitsuka; Wook-Dong Kim
Journal:  Curr Pharm Biotechnol       Date:  2010-04       Impact factor: 2.837

Review 7.  Clarification technologies for monoclonal antibody manufacturing processes: Current state and future perspectives.

Authors:  Nripen Singh; Abhiram Arunkumar; Srinivas Chollangi; Zhijun George Tan; Michael Borys; Zheng Jian Li
Journal:  Biotechnol Bioeng       Date:  2015-09-29       Impact factor: 4.530

8.  Dewatering of algal suspension using microfiltration with cross flow in the presence of magnetite as a filter aid.

Authors:  Hidemi Kitani; Mikihide Demura; Shintaro Morisada; Keisuke Ohto; Hidetaka Kawakita
Journal:  Biotechnol Prog       Date:  2020-02-16

Review 9.  Advances in recombinant antibody manufacturing.

Authors:  Renate Kunert; David Reinhart
Journal:  Appl Microbiol Biotechnol       Date:  2016-03-03       Impact factor: 4.813

  9 in total

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