Literature DB >> 3429338

Biosynthesis of napyradiomycins.

K Shiomi1, H Iinuma, H Naganawa, K Isshiki, T Takeuchi, H Umezawa.   

Abstract

Biosynthetic studies on napyradiomycins were carried out based on the incorporation of [2-13C]acetate and [1,2-13C]acetate. The alignment of acetate units suggested that the B and C rings of napyradiomycins are derived from a pentaketide, while ring A and the side chain may be synthesized from mevalonate.

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Year:  1987        PMID： 3429338     DOI： 10.7164/antibiotics.40.1740

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  13 in total

1.  Cloning and characterization of 1-deoxy-D-xylulose 5-phosphate synthase from Streptomyces sp. Strain CL190, which uses both the mevalonate and nonmevalonate pathways for isopentenyl diphosphate biosynthesis.

Authors:  T Kuzuyama; M Takagi; S Takahashi; H Seto
Journal:  J Bacteriol       Date:  2000-02       Impact factor: 3.490

2.  Natural products as inspiration for the development of new synthetic methods.

Authors:  Zhiqiang Ma; Chuo Chen
Journal:  J Chin Chem Soc       Date:  2017-08-09       Impact factor: 1.967

3.  Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate.

Authors:  M Rohmer; M Knani; P Simonin; B Sutter; H Sahm
Journal:  Biochem J       Date:  1993-10-15       Impact factor: 3.857

4.  Total Enzyme Syntheses of Napyradiomycins A1 and B1.

Authors:  Shaun M K McKinnie; Zachary D Miles; Peter A Jordan; Takayoshi Awakawa; Henry P Pepper; Lauren A M Murray; Jonathan H George; Bradley S Moore
Journal:  J Am Chem Soc       Date:  2018-12-14       Impact factor: 15.419

5.  A gene cluster for the mevalonate pathway from Streptomyces sp. Strain CL190.

Authors:  M Takagi; T Kuzuyama; S Takahashi; H Seto
Journal:  J Bacteriol       Date:  2000-08       Impact factor: 3.490

6.  Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: identification and heterologous expression of the gene cluster.

Authors:  Takashi Kawasaki; Yutaka Hayashi; Tomohisa Kuzuyama; Kazuo Furihata; Nobuya Itoh; Haruo Seto; Tohru Dairi
Journal:  J Bacteriol       Date:  2006-02       Impact factor: 3.490

7.  Formation of the pyridazine natural product azamerone by biosynthetic rearrangement of an aryl diazoketone.

Authors:  Jaclyn M Winter; Ariane L Jansma; Tracy M Handel; Bradley S Moore
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

8.  Purification, characterization, and cloning of a eubacterial 3-hydroxy-3-methylglutaryl coenzyme A reductase, a key enzyme involved in biosynthesis of terpenoids.

Authors:  S Takahashi; T Kuzuyama; H Seto
Journal:  J Bacteriol       Date:  1999-02       Impact factor: 3.490

9.  Napyradiomycins CNQ525.510B and A80915C target the Hsp90 paralogue Grp94.

Authors:  Lauge Farnaes; James J La Clair; William Fenical
Journal:  Org Biomol Chem       Date:  2013-11-29       Impact factor: 3.876

10.  Bactericidal kinetics of marine-derived napyradiomycins against contemporary methicillin-resistant Staphylococcus aureus.

Authors:  Nina M Haste; Lauge Farnaes; Varahenage R Perera; William Fenical; Victor Nizet; Mary E Hensler
Journal:  Mar Drugs       Date:  2011-04-21       Impact factor: 6.085
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