Literature DB >> 3429238

The production of 99mTc-labeled conjugated antibodies using a cyclam-based bifunctional chelating agent.

J Franz1, W A Volkert, E K Barefield, R A Holmes.   

Abstract

A bifunctional chelating agent (BFCA) based on a macrocyclic amine, cyclam, was used to form specifically 99mTc labeled rabbit-anti-HSA-antibodies. This study demonstrates the feasibility of forming a highly stable cyclam-based 99mTc-BFCA with its subsequent conjugation to antibodies.

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Year:  1987        PMID: 3429238     DOI: 10.1016/0883-2897(87)90027-4

Source DB:  PubMed          Journal:  Int J Rad Appl Instrum B        ISSN: 0883-2897


  2 in total

1.  Production of a bifunctional hybrid molecule B72.3/metallothionein-1 by protein engineering.

Authors:  J Xiang; J Koropatnick; Y Qi; X Luo; T Moyana; K Li; Y Chen
Journal:  Immunology       Date:  1993-04       Impact factor: 7.397

Review 2.  Radiolabeling with technetium-99m to study high-capacity and low-capacity biochemical systems.

Authors:  W C Eckelman
Journal:  Eur J Nucl Med       Date:  1995-03
  2 in total

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