| Literature DB >> 3429219 |
F Carella1, E Riva, L Morandi, E Cappiello, A Mangoni.
Abstract
The case of a 69-year-old woman who developed muscle weakness on chronic amiodarone treatment is reported. Muscle biopsy showed vacuolar alterations and a marked accumulation of amiodarone and of its metabolite desethylamiodarone was found in the muscle sample despite normal blood levels. Amiodarone-induced morphological alterations of the muscle may be related to the actual tissue concentration rather than to the blood level.Entities:
Mesh:
Substances:
Year: 1987 PMID: 3429219 DOI: 10.1007/BF02333668
Source DB: PubMed Journal: Ital J Neurol Sci ISSN: 0392-0461