| Literature DB >> 3429130 |
L Otvos1, B Dietzschold, L Kisfaludy.
Abstract
Boc-amino acid pentafluorophenyl esters have been successfully used in solid-phase peptide synthesis. The coupling rates and the purity of the products are comparable to those with the symmetrical anhydrides. These active esters require modified Merrifield resin, polar medium for coupling and in some cases, base catalysis.Entities:
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Year: 1987 PMID: 3429130 DOI: 10.1111/j.1399-3011.1987.tb03359.x
Source DB: PubMed Journal: Int J Pept Protein Res ISSN: 0367-8377