Literature DB >> 34282184

The effect of eligibility for antiretroviral therapy on body mass index and blood pressure in KwaZulu-Natal, South Africa.

Aditi Kuber1, Anna Reuter2,3, Pascal Geldsetzer4,5, Natsayi Chimbindi6, Mosa Moshabela6,7, Frank Tanser6,7,8,9, Till Bärnighausen6,5, Sebastian Vollmer1.   

Abstract

We use a regression discontinuity design to estimate the causal effect of antiretroviral therapy (ART) eligibility according to national treatment guidelines of South Africa on two risk factors for cardiovascular disease, body mass index (BMI) and blood pressure. We combine survey data collected in 2010 in KwaZulu-Natal, South Africa, with clinical data on ART. We find that early ART eligibility significantly reduces systolic and diastolic blood pressure. We do not find any significant effects on BMI. The effect on blood pressure can be detected up to three years after becoming eligible for ART.
© 2021. The Author(s).

Entities:  

Year:  2021        PMID: 34282184     DOI: 10.1038/s41598-021-94057-z

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  31 in total

1.  HIV infection in older adults in sub-Saharan Africa: extrapolating prevalence from existing data.

Authors:  Joel Negin; Robert G Cumming
Journal:  Bull World Health Organ       Date:  2010-08-27       Impact factor: 9.408

2.  HIV surveys in older adults: better data, better health.

Authors:  Sebastian Vollmer; Tobias Alfven; Jude Padayachy; Kenneth Harttgen; Peter D Ghys; Till Bärnighausen
Journal:  Lancet HIV       Date:  2015-01-29       Impact factor: 12.767

3.  Continued improvement in survival among HIV-infected individuals with newer forms of highly active antiretroviral therapy.

Authors:  Viviane D Lima; Robert S Hogg; P Richard Harrigan; David Moore; Benita Yip; Evan Wood; Julio S G Montaner
Journal:  AIDS       Date:  2007-03-30       Impact factor: 4.177

4.  Aging with HIV in Africa: the challenges of living longer.

Authors:  Joel Negin; Till Bärnighausen; Jens D Lundgren; Edward J Mills
Journal:  AIDS       Date:  2012-07-31       Impact factor: 4.177

Review 5.  Relative risk of cardiovascular disease among people living with HIV: a systematic review and meta-analysis.

Authors:  F M Islam; J Wu; J Jansson; D P Wilson
Journal:  HIV Med       Date:  2012-03-14       Impact factor: 3.180

6.  The impact of antiretroviral treatment on the age composition of the HIV epidemic in sub-Saharan Africa.

Authors:  Jan A C Hontelez; Sake J de Vlas; Rob Baltussen; Marie-Louise Newell; Roel Bakker; Frank Tanser; Mark Lurie; Till Bärnighausen
Journal:  AIDS       Date:  2012-07-31       Impact factor: 4.177

7.  Changes in Cardiovascular Disease Risk Factors With Immediate Versus Deferred Antiretroviral Therapy Initiation Among HIV-Positive Participants in the START (Strategic Timing of Antiretroviral Treatment) Trial.

Authors:  Jason V Baker; Shweta Sharma; Amit C Achhra; Jose Ignacio Bernardino; Johannes R Bogner; Daniel Duprez; Sean Emery; Brian Gazzard; Jonathan Gordin; Greg Grandits; Andrew N Phillips; Siegfried Schwarze; Elsayed Z Soliman; Stephen A Spector; Giuseppe Tambussi; Jens Lundgren
Journal:  J Am Heart Assoc       Date:  2017-05-22       Impact factor: 5.501

8.  Global Burden of Atherosclerotic Cardiovascular Disease in People Living With HIV: Systematic Review and Meta-Analysis.

Authors:  Anoop S V Shah; Dominik Stelzle; Kuan Ken Lee; Eduard J Beck; Shirjel Alam; Sarah Clifford; Chris T Longenecker; Fiona Strachan; Shashwatee Bagchi; William Whiteley; Sanjay Rajagopalan; Shyamasundaran Kottilil; Harish Nair; David E Newby; David A McAllister; Nicholas L Mills
Journal:  Circulation       Date:  2018-09-11       Impact factor: 29.690

9.  Life expectancies of South African adults starting antiretroviral treatment: collaborative analysis of cohort studies.

Authors:  Leigh F Johnson; Joel Mossong; Rob E Dorrington; Michael Schomaker; Christopher J Hoffmann; Olivia Keiser; Matthew P Fox; Robin Wood; Hans Prozesky; Janet Giddy; Daniela Belen Garone; Morna Cornell; Matthias Egger; Andrew Boulle
Journal:  PLoS Med       Date:  2013-04-09       Impact factor: 11.069

Review 10.  HIV and cardiovascular disease.

Authors:  Kaku So-Armah; Laura A Benjamin; Gerald S Bloomfield; Matthew J Feinstein; Priscilla Hsue; Benson Njuguna; Matthew S Freiberg
Journal:  Lancet HIV       Date:  2020-04       Impact factor: 16.070

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