| Literature DB >> 34279974 |
Rahimeh B Atashgah1,2, Amir Ghasemi3, Mohammad Raoufi3,4, Mohammad-Amin Abdollahifar5, Steven Zanganeh6, Hossein Nejadnik7, Alieh Abdollahi2, Shahriar Sharifi8, Baltazar Lea1, Miguel Cuerva9, Mehdi Akbarzadeh10, Carmen Alvarez-Lorenzo11, Seyed Nasser Ostad2, Andrea S Theus12, Doris L LaRock13, Christopher N LaRock13, Vahid Serpooshan12,14,15, Rouzbeh Sarrafi16, Ki-Bum Lee17, Hojatollah Vali18, Holger Schönherr4, Lisa Gould19,20, Pablo Taboada1, Morteza Mahmoudi8,21,22.
Abstract
Current treatment of chronic wounds has been critically limited by various factors, including bacterial infection, biofilm formation, impaired angiogenesis, and prolonged inflammation. Addressing these challenges, we developed a multifunctional wound dressing-based three-pronged approach for accelerating wound healing. The multifunctional wound dressing, composed of nanofibers, functional nanoparticles, natural biopolymers, and selected protein and peptide, can target multiple endogenous repair mechanisms and represents a promising alternative to current wound healing products.Entities:
Keywords: chronic wounds; endogenous repair; multifunctional wound dressing; nanomedicine
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Year: 2021 PMID： 34279974 DOI： 10.1021/acs.molpharmaceut.1c00400
Source DB: PubMed Journal: Mol Pharm ISSN： 1543-8384 Impact factor: 4.939