Literature DB >> 34279840

Curcumin and Piperine in COVID-19: A Promising Duo to the Rescue?

Mahsa Miryan1,2, Davood Soleimani3, Gholamreza Askari4,5,6, Tannaz Jamialahmadi7,8, Paul C Guest9, Mohammad Bagherniya10,11,12, Amirhossein Sahebkar13,14,15,16.   

Abstract

COVID-19 is now pandemic throughout the world, and scientists are searching for effective therapies to prevent or treat the disease. The combination of curcumin and piperine is a potential option for the management of COVID-19 based on several mechanisms including antiviral, anti-inflammatory, immunomodulatory, antifibrotic, and antioxidant effects. Here, we describe the probable mechanism of curcumin-piperine against COVID-19. Administration of curcumin-piperine combination appears as a potential strategy to counterbalance the pathophysiological features of COVID-19 including inflammation. The optimal dose and duration of curcumin-piperine supplementation should be determined in the future.
© 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.

Entities:  

Keywords:  COVID-19; Coronavirus; Curcumin; Curcumin-piperine; Piperine

Mesh：

Substances：

Year:  2021        PMID： 34279840     DOI： 10.1007/978-3-030-71697-4_16

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  48 in total

1.  Primary severe acute respiratory syndrome coronavirus infection limits replication but not lung inflammation upon homologous rechallenge.

Authors:  Candice Clay; Nathan Donart; Ndingsa Fomukong; Jennifer B Knight; Wanli Lei; Lance Price; Fletcher Hahn; Jesse Van Westrienen; Kevin S Harrod
Journal:  J Virol       Date:  2012-02-15       Impact factor: 5.103

2.  A Novel Coronavirus Emerging in China - Key Questions for Impact Assessment.

Authors:  Vincent J Munster; Marion Koopmans; Neeltje van Doremalen; Debby van Riel; Emmie de Wit
Journal:  N Engl J Med       Date:  2020-01-24       Impact factor: 91.245

Review 3.  Immune modulation by curcumin: The role of interleukin-10.

Authors:  Hamid Mollazadeh; Arrigo F G Cicero; Christopher N Blesso; Matteo Pirro; Muhammed Majeed; Amirhossein Sahebkar
Journal:  Crit Rev Food Sci Nutr       Date:  2017-09-06       Impact factor: 11.176

4.  Characterization of two new electrophoretic variants of human triosephosphate isomerase: stability, kinetic, and immunological properties.

Authors:  J Asakawa; H W Mohrenweiser
Journal:  Biochem Genet       Date:  1982-02       Impact factor: 1.890

5.  Cancer chemopreventive activity of diversin from Ferula diversivittata in vitro and in vivo.

Authors:  M Iranshahi; A Sahebkar; S T Hosseini; M Takasaki; T Konoshima; H Tokuda
Journal:  Phytomedicine       Date:  2009-07-03       Impact factor: 5.340

Review 6.  Effects of curcumin on mitochondria in neurodegenerative diseases.

Authors:  Hossein Bagheri; Faezeh Ghasemi; George E Barreto; Rouhullah Rafiee; Thozhukat Sathyapalan; Amirhossein Sahebkar
Journal:  Biofactors       Date:  2019-10-03       Impact factor: 6.113

7.  Novel coronavirus (SARS-CoV-2) epidemic: a veterinary perspective.

Authors:  Alessio Lorusso; Paolo Calistri; Antonio Petrini; Giovanni Savini; Nicola Decaro
Journal:  Vet Ital       Date:  2020-04-24       Impact factor: 1.101

Review 8.  Molecular mechanisms of severe acute respiratory syndrome (SARS).

Authors:  David A Groneberg; Rolf Hilgenfeld; Peter Zabel
Journal:  Respir Res       Date:  2005-01-20

9.  Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series.

Authors:  Xiao-Wei Xu; Xiao-Xin Wu; Xian-Gao Jiang; Kai-Jin Xu; Ling-Jun Ying; Chun-Lian Ma; Shi-Bo Li; Hua-Ying Wang; Sheng Zhang; Hai-Nv Gao; Ji-Fang Sheng; Hong-Liu Cai; Yun-Qing Qiu; Lan-Juan Li
Journal:  BMJ       Date:  2020-02-19

10.  Nano-curcumin therapy, a promising method in modulating inflammatory cytokines in COVID-19 patients.

Authors:  Hamed Valizadeh; Samaneh Abdolmohammadi-Vahid; Svetlana Danshina; Mehmet Ziya Gencer; Ali Ammari; Armin Sadeghi; Leila Roshangar; Saeed Aslani; Abdolreza Esmaeilzadeh; Mahnaz Ghaebi; Sepehr Valizadeh; Majid Ahmadi
Journal:  Int Immunopharmacol       Date:  2020-10-20       Impact factor: 4.932
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  3 in total

1.  The efficacy of curcumin-piperine co-supplementation on clinical symptoms, duration, severity, and inflammatory factors in COVID-19 outpatients: a randomized double-blind, placebo-controlled trial.

Authors:  Gholamreza Askari; Amirhossein Sahebkar; Davood Soleimani; Atena Mahdavi; Sahar Rafiee; Muhammed Majeed; Farzin Khorvash; Bijan Iraj; Mahshid Elyasi; Mohammad Hossein Rouhani; Mohammad Bagherniya
Journal:  Trials       Date:  2022-06-06       Impact factor: 2.728

Review 2.  Advances in Immunosuppressive Agents Based on Signal Pathway.

Authors:  Zhiqing Xu; Ming Chu
Journal:  Front Pharmacol       Date:  2022-05-26       Impact factor: 5.988

Review 3.  Pharmaceutical Prospects of Curcuminoids for the Remedy of COVID-19: Truth or Myth.

Authors:  Yaw-Syan Fu; Wan-Yi Ho; Ning Kang; May-Jywan Tsai; Jingyi Wu; Liyue Huang; Ching-Feng Weng
Journal:  Front Pharmacol       Date:  2022-04-14       Impact factor: 5.988
  3 in total

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