Xiao-Yan He1, Cai-Lan Hou2, Zhuo-Hui Huang3, Ying-Hua Huang4, Ji-Jie Zhang5, Zhong-Lei Wang6, Fu-Jun Jia7. 1. The Second School of Clinical Medicine, Southern Medical University, Guangdong Province, Guangzhou, China; Guangdong Provincial People's Hospital, Guangdong Academy of MedicalSciences, Guangdong Mental Health Center, Guangdong Province, China; Liuzhou Worker's Hospital, Liuzhou, Guangxi Province, China. 2. The Second School of Clinical Medicine, Southern Medical University, Guangdong Province, Guangzhou, China; Guangdong Provincial People's Hospital, Guangdong Academy of MedicalSciences, Guangdong Mental Health Center, Guangdong Province, China. Electronic address: houcl1975@163.com. 3. Guangdong Provincial People's Hospital, Guangdong Academy of MedicalSciences, Guangdong Mental Health Center, Guangdong Province, China. 4. Guangdong Second People's Hospital, Guangzhou, Guangdong Province, China. 5. The Second School of Clinical Medicine, Southern Medical University, Guangdong Province, Guangzhou, China; Guangdong Provincial People's Hospital, Guangdong Academy of MedicalSciences, Guangdong Mental Health Center, Guangdong Province, China. 6. ShenzhenKangNing Hospital, Shenzhen, Guangdong Province, China. 7. The Second School of Clinical Medicine, Southern Medical University, Guangdong Province, Guangzhou, China; Guangdong Provincial People's Hospital, Guangdong Academy of MedicalSciences, Guangdong Mental Health Center, Guangdong Province, China. Electronic address: jiafujun@126.com.
Abstract
AIM: The present study was designed to assess the role of family function and social support in the context of different phases of schizophrenia. METHODS: First-episode patients with experiences of schizophrenia (FEP), ultra-high risk for psychosis (UHR), first-degree relatives (FDR) of patients with experiences of schizophrenia, and healthy controls (HC) (40 per group) were subjected to in-person clinical interviews. The results of these interviews were then used to gauge social support and family function using the Perceived Social Support Scale (PSSS) and the Family Adaptability and Cohesion Scales (FACESII-CV). Data were analyzed through ANCOVA, correlation analysis and logistic regression analyses. RESULTS: We found that family function and social support showed a approximately gradual downward trend through the HC, FDR, UHR, and FEP groups but no significant differences were found in the family function of the FDR, UHR and FDR group. Logistic regression analyses indicated that UHR group patients exhibited decreased family support and family cohesion relative to members of the HC group, but had greater perceived social support than did members of the FEP group. Results for members of the FDR group were in line with those of members of the UHR group. CONCLUSIONS: These findings suggested that both UHR and FDR individuals experience impaired family functionality and social support which expanded the understanding of the psychological characteristics of the prodromal period of schizophrenia. Further explorations are warranted to develop optimal psychosocial interventions.
AIM: The present study was designed to assess the role of family function and social support in the context of different phases of schizophrenia. METHODS: First-episode patients with experiences of schizophrenia (FEP), ultra-high risk for psychosis (UHR), first-degree relatives (FDR) of patients with experiences of schizophrenia, and healthy controls (HC) (40 per group) were subjected to in-person clinical interviews. The results of these interviews were then used to gauge social support and family function using the Perceived Social Support Scale (PSSS) and the Family Adaptability and Cohesion Scales (FACESII-CV). Data were analyzed through ANCOVA, correlation analysis and logistic regression analyses. RESULTS: We found that family function and social support showed a approximately gradual downward trend through the HC, FDR, UHR, and FEP groups but no significant differences were found in the family function of the FDR, UHR and FDR group. Logistic regression analyses indicated that UHR group patients exhibited decreased family support and family cohesion relative to members of the HC group, but had greater perceived social support than did members of the FEP group. Results for members of the FDR group were in line with those of members of the UHR group. CONCLUSIONS: These findings suggested that both UHR and FDR individuals experience impaired family functionality and social support which expanded the understanding of the psychological characteristics of the prodromal period of schizophrenia. Further explorations are warranted to develop optimal psychosocial interventions.