Literature DB >> 34274307

Increasing Guideline-Concordant Durations of Antibiotic Therapy for Acute Otitis Media.

Holly M Frost1, Yingbo Lou2, Amy Keith3, Andrew Byars4, Timothy C Jenkins5.   

Abstract

OBJECTIVE: To compare the effectiveness of 2 interventions in improving prescribing of guideline-concordant durations of therapy for acute otitis media (AOM). STUDY
DESIGN: This was a quasi-experimental mixed methods analysis that compared a bundled quality improvement intervention consisting of individualized audit and feedback, education, and electronic health record (EHR) changes to an EHR-only intervention. The bundle was implemented in 3 pediatric clinics from January to August 2020 and an EHR-only intervention was implemented in 6 family medicine clinics. The primary outcome measure was prescription of an institutional guideline-concordant 5-day duration of therapy for children ≥2 years of age with uncomplicated AOM. Propensity score matching and differences-in-differences analysis weighted with inverse probability of treatment were completed. Implementation outcomes were assessed using the Reach, Effectiveness, Adoption, Implementation, Maintenance Framework. Balance measures included treatment failure and recurrence.
RESULTS: In total, 1017 encounters for AOM were included from February 2019 to August 2020. Guideline-concordant prescribing increased from 14.4% to 63.8% (difference = 49.4%) in clinics that received the EHR-only intervention and from 10.6% to 85.2% (difference = 74.6%) in clinics that received the bundled intervention. In the adjusted analysis, the bundled intervention improved guideline-concordant durations by an additional 26.4% (P < .01) compared with the EHR-only intervention. Providers identified EHR-prescription field changes as the most helpful components. There were no differences in treatment failure or recurrence rates between baseline and either intervention.
CONCLUSIONS: Both interventions resulted in improved prescribing of guideline-concordant durations of antibiotics. The bundled intervention improved prescribing more than an EHR-only intervention and was acceptable to providers.
Copyright © 2021 Elsevier Inc. All rights reserved.

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Year:  2021        PMID: 34274307      PMCID: PMC8792957          DOI: 10.1016/j.jpeds.2021.07.016

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  18 in total

Review 1.  Evaluating the public health impact of health promotion interventions: the RE-AIM framework.

Authors:  R E Glasgow; T M Vogt; S M Boles
Journal:  Am J Public Health       Date:  1999-09       Impact factor: 9.308

2.  The diagnosis and management of acute otitis media.

Authors:  Allan S Lieberthal; Aaron E Carroll; Tasnee Chonmaitree; Theodore G Ganiats; Alejandro Hoberman; Mary Anne Jackson; Mark D Joffe; Donald T Miller; Richard M Rosenfeld; Xavier D Sevilla; Richard H Schwartz; Pauline A Thomas; David E Tunkel
Journal:  Pediatrics       Date:  2013-02-25       Impact factor: 7.124

3.  Implementation of an institution-specific antimicrobial stewardship smartphone application.

Authors:  Heather L Young; Katherine C Shihadeh; Alisha A Skinner; Bryan C Knepper; Jeffrey Sankoff; Jeremy Voros; Timothy C Jenkins
Journal:  Infect Control Hosp Epidemiol       Date:  2018-06-21       Impact factor: 3.254

Review 4.  Microbiome, antibiotics and irritable bowel syndrome.

Authors:  O F Ahmad; A Akbar
Journal:  Br Med Bull       Date:  2016-10-13       Impact factor: 4.291

Review 5.  Community-associated Clostridium difficile infection and antibiotics: a meta-analysis.

Authors:  Abhishek Deshpande; Vinay Pasupuleti; Priyaleela Thota; Chaitanya Pant; David D K Rolston; Thomas J Sferra; Adrian V Hernandez; Curtis J Donskey
Journal:  J Antimicrob Chemother       Date:  2013-04-25       Impact factor: 5.790

6.  Core Elements of Outpatient Antibiotic Stewardship.

Authors:  Guillermo V Sanchez; Katherine E Fleming-Dutra; Rebecca M Roberts; Lauri A Hicks
Journal:  MMWR Recomm Rep       Date:  2016-11-11

7.  Association of Broad- vs Narrow-Spectrum Antibiotics With Treatment Failure, Adverse Events, and Quality of Life in Children With Acute Respiratory Tract Infections.

Authors:  Jeffrey S Gerber; Rachael K Ross; Matthew Bryan; A Russell Localio; Julia E Szymczak; Richard Wasserman; Darlene Barkman; Folasade Odeniyi; Kathryn Conaboy; Louis Bell; Theoklis E Zaoutis; Alexander G Fiks
Journal:  JAMA       Date:  2017-12-19       Impact factor: 56.272

Review 8.  Short-course antibiotics for acute otitis media.

Authors:  Anita Kozyrskyj; Terry P Klassen; Michael Moffatt; Krystal Harvey
Journal:  Cochrane Database Syst Rev       Date:  2010-09-08

9.  A Statewide Antibiotic Stewardship Collaborative to Improve the Diagnosis and Treatment of Urinary Tract and Skin and Soft Tissue Infections.

Authors:  Timothy C Jenkins; Teresa Hulett; Bryan C Knepper; Katherine C Shihadeh; Marc J Meyer; Gerard R Barber; John H Hammer; Heidi L Wald
Journal:  Clin Infect Dis       Date:  2018-10-30       Impact factor: 9.079

10.  Effect of an outpatient antimicrobial stewardship intervention on broad-spectrum antibiotic prescribing by primary care pediatricians: a randomized trial.

Authors:  Jeffrey S Gerber; Priya A Prasad; Alexander G Fiks; A Russell Localio; Robert W Grundmeier; Louis M Bell; Richard C Wasserman; Ron Keren; Theoklis E Zaoutis
Journal:  JAMA       Date:  2013-06-12       Impact factor: 56.272

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  1 in total

1.  Caregiver perspectives and preferences for acute otitis media management.

Authors:  Holly M Frost; Amy Keith; Thresia Sebastian; Timothy C Jenkins
Journal:  Antimicrob Steward Healthc Epidemiol       Date:  2021-12-22
  1 in total

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