Literature DB >> 3427420

Blood-brain barrier permeability to horseradish peroxidase in twitcher and cuprizone-intoxicated mice.

A Kondo1, T Nakano, K Suzuki.   

Abstract

The status of blood-brain barrier (BBB) permeability was investigated in the twitcher, an authentic murine model of globoid cell leukodystrophy (GLD, Krabbe disease) and cuprizone-intoxicated mice. Although extensive demyelination was noted in the CNS of both mice and additionally, macrophage infiltration was pronounced in the twitcher, BBB remained intact to horseradish peroxidase. Thus, the change of microenvironment caused by demyelination is not necessarily a responsible factor for increased BBB permeability in the inflammatory demyelinating conditions.

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Year:  1987        PMID： 3427420     DOI： 10.1016/0006-8993(87)90499-9

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  35 in total

1.  Intravenous administration of human embryonic stem cell-derived neural precursor cells attenuates cuprizone-induced central nervous system (CNS) demyelination.

Authors:  S J Crocker; R Bajpai; C S Moore; R F Frausto; G D Brown; R R Pagarigan; J L Whitton; A V Terskikh
Journal:  Neuropathol Appl Neurobiol       Date:  2011-10       Impact factor: 8.090

2.  The Effect of Melatonin on Behavioral, Molecular, and Histopathological Changes in Cuprizone Model of Demyelination.

Authors:  Gelareh Vakilzadeh; Fariba Khodagholi; Tahereh Ghadiri; Amir Ghaemi; Farshid Noorbakhsh; Mohammad Sharifzadeh; Ali Gorji
Journal:  Mol Neurobiol       Date:  2015-08-27       Impact factor: 5.590

3.  MHC class II exacerbates demyelination in vivo independently of T cells.

Authors:  Meenaxi M Hiremath; Vivian S Chen; Kinuko Suzuki; Jenny P Y Ting; Glenn K Matsushima
Journal:  J Neuroimmunol       Date:  2008-10-15       Impact factor: 3.478

4.  Insulin-like growth factor-1 inhibits mature oligodendrocyte apoptosis during primary demyelination.

Authors:  J L Mason; P Ye; K Suzuki; A J D'Ercole; G K Matsushima
Journal:  J Neurosci       Date:  2000-08-01       Impact factor: 6.167

5.  Peripherally derived FGF21 promotes remyelination in the central nervous system.

Authors:  Mariko Kuroda; Rieko Muramatsu; Noriko Maedera; Yoshihisa Koyama; Machika Hamaguchi; Harutoshi Fujimura; Mari Yoshida; Morichika Konishi; Nobuyuki Itoh; Hideki Mochizuki; Toshihide Yamashita
Journal:  J Clin Invest       Date:  2017-08-21       Impact factor: 14.808

6.  Deleterious role of IFNgamma in a toxic model of central nervous system demyelination.

Authors:  Paula Maña; David Liñares; Sue Fordham; Maria Staykova; David Willenborg
Journal:  Am J Pathol       Date:  2006-05       Impact factor: 4.307

Review 7.  Current advancements in promoting remyelination in multiple sclerosis.

Authors:  David Kremer; Rainer Akkermann; Patrick Küry; Ranjan Dutta
Journal:  Mult Scler       Date:  2018-10-01       Impact factor: 6.312

8.  Cortical demyelination is prominent in the murine cuprizone model and is strain-dependent.

Authors:  Thomas Skripuletz; Maren Lindner; Alexandra Kotsiari; Niklas Garde; Jantje Fokuhl; Franziska Linsmeier; Corinna Trebst; Martin Stangel
Journal:  Am J Pathol       Date:  2008-03-18       Impact factor: 4.307

9.  Effects of acute and repeated exposure to lipopolysaccharide on cytokine and corticosterone production during remyelination.

Authors:  Daniella Urbach-Ross; Alexander W Kusnecov
Journal:  Brain Behav Immun       Date:  2007-05-08       Impact factor: 7.217

10.  Microglial recruitment, activation, and proliferation in response to primary demyelination.

Authors:  Leah T Remington; Alicia A Babcock; Simone P Zehntner; Trevor Owens
Journal:  Am J Pathol       Date:  2007-05       Impact factor: 4.307
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