Tochukwu F Ilodibia1, James O Odia2. 1. Division of Cardiology, Department of Internal Medicine, University of Port Harcourt Teaching Hospital, East-West Road, Opposite Alakahia Junction, Rivers State, PMB, 6173, Nigeria. Electronic address: baronaugust@yahoo.com. 2. Division of Cardiology, Department of Internal Medicine, University of Port Harcourt Teaching Hospital, East-West Road, Opposite Alakahia Junction, Rivers State, PMB, 6173, Nigeria.
Abstract
BACKGROUND: The Seattle Criteria (SC) and International Criteria (IC) were both developed for cardiovascular pre-participation screening in young athletes. Neither set of Criteria has been systematically evaluated in high level indigenous black African athletes. OBJECTIVES: (1) To determine the pattern of ECG findings in athletes of the University of Port Harcourt, Nigeria; (2) To determine the predictors of altered repolarization in these athletes; and (3) To evaluate the diagnostic performance of the SC and IC in these athletes. METHODS: 77 athletes (42 males, 35 females) without any known cardiovascular disease were recruited alongside 78 similarly healthy non-athletic controls (44 males, 34 females). The two groups were matched for age, sex, and body mass index. Clinical assessment was according to the Lausanne Recommendations. All subjects underwent electrocardiography and echocardiography. Analysis with the IC was retrospective. RESULTS: The most common physiological finding in the athletes was sinus bradycardia (n = 37; 48.1%). Early repolarization pattern, ERP (n = 27, 35.1% with SC; n = 42, 54.5% with IC), and dome-shaped ST-segment elevation with T-wave inversion (DSSTWI) in leads V1-4 (n = 21, 29.3% with both criteria), were also prevalent. Compared to controls, only male sex (adjusted odds ratio 2.89, 1.05 to 7.97, p = .040 with SC; OR 2.57, 1.19 to 5.53, p = .016 with IC) and ECG LVH (OR 2.82, 1.18 to 6.75, p = .020 with SC alone) independently predicted ERP, while athletic status (OR 4.76, 1.66 to 13.68, p = .004 with both criteria) alone had a significant multivariate association with DSSTWI. Three athletes (3.9%) had abnormal ECGs while two (2.6%) had major echocardiographic abnormalities. The sensitivity, specificity and accuracy of the SC for structural cardiac disease in the athletes were 50.0% (1.3 to 98.7), 97.3% (90.7 to 99.7) and 96.1% (89.0 to 99.2) respectively. The respective figures for the IC were 50.0% (1.3 to 98.7), 98.7% (92.8 to 100) and 97.4% (90.9 to 99.7). CONCLUSION: Both criteria showed high accuracy in this Black African cohort with a high frequency of electrocardiographic repolarization changes. While ERP seems to be primarily related to black ethnicity, DSSTWI appears to be a bona fide marker of Athlete's Heart in blacks.
BACKGROUND: The Seattle Criteria (SC) and International Criteria (IC) were both developed for cardiovascular pre-participation screening in young athletes. Neither set of Criteria has been systematically evaluated in high level indigenous black African athletes. OBJECTIVES: (1) To determine the pattern of ECG findings in athletes of the University of Port Harcourt, Nigeria; (2) To determine the predictors of altered repolarization in these athletes; and (3) To evaluate the diagnostic performance of the SC and IC in these athletes. METHODS: 77 athletes (42 males, 35 females) without any known cardiovascular disease were recruited alongside 78 similarly healthy non-athletic controls (44 males, 34 females). The two groups were matched for age, sex, and body mass index. Clinical assessment was according to the Lausanne Recommendations. All subjects underwent electrocardiography and echocardiography. Analysis with the IC was retrospective. RESULTS: The most common physiological finding in the athletes was sinus bradycardia (n = 37; 48.1%). Early repolarization pattern, ERP (n = 27, 35.1% with SC; n = 42, 54.5% with IC), and dome-shaped ST-segment elevation with T-wave inversion (DSSTWI) in leads V1-4 (n = 21, 29.3% with both criteria), were also prevalent. Compared to controls, only male sex (adjusted odds ratio 2.89, 1.05 to 7.97, p = .040 with SC; OR 2.57, 1.19 to 5.53, p = .016 with IC) and ECG LVH (OR 2.82, 1.18 to 6.75, p = .020 with SC alone) independently predicted ERP, while athletic status (OR 4.76, 1.66 to 13.68, p = .004 with both criteria) alone had a significant multivariate association with DSSTWI. Three athletes (3.9%) had abnormal ECGs while two (2.6%) had major echocardiographic abnormalities. The sensitivity, specificity and accuracy of the SC for structural cardiac disease in the athletes were 50.0% (1.3 to 98.7), 97.3% (90.7 to 99.7) and 96.1% (89.0 to 99.2) respectively. The respective figures for the IC were 50.0% (1.3 to 98.7), 98.7% (92.8 to 100) and 97.4% (90.9 to 99.7). CONCLUSION: Both criteria showed high accuracy in this Black African cohort with a high frequency of electrocardiographic repolarization changes. While ERP seems to be primarily related to black ethnicity, DSSTWI appears to be a bona fide marker of Athlete's Heart in blacks.