Sidsel Høgh-Poulsen1, Jane M Bendix2, Maria Mieskiewicz Larsen3, Rie Adser Virkus4, Anne Dsane Andersen5, Tine Dalsgaard Clausen6, Ellen Christine Leth Løkkegaard7, Paul Bryde Axelsson8. 1. Department of Gynaecology and Obstetrics, Nordsjællands Hospital Hillerød, Dyrehavevej 29, 3400 Hillerød, Denmark. Electronic address: sidsel.poulsen@hotmail.com. 2. Department of Gynaecology and Obstetrics, Nordsjællands Hospital Hillerød, Dyrehavevej 29, 3400 Hillerød, Denmark. Electronic address: Jane.Bendix@regionh.dk. 3. Copenhagen Centre for Health Research in Humanities (CoRe), Saxo Institute Copenhagen University. Karen Blixens Vej 8, 2300 Copenhagen, Denmark. Electronic address: maria.larsen@hum.ku.dk. 4. Department of Gynaecology and Obstetrics, Nordsjællands Hospital Hillerød, Dyrehavevej 29, 3400 Hillerød, Denmark. Electronic address: rie.virkus@regionh.dk. 5. Department of Gynaecology and Obstetrics, Nordsjællands Hospital Hillerød, Dyrehavevej 29, 3400 Hillerød, Denmark. Electronic address: anne.dsane.andersen@regionh.dk. 6. Department of Gynaecology and Obstetrics, Nordsjællands Hospital Hillerød, Dyrehavevej 29, 3400 Hillerød, Denmark. Electronic address: tine.clausen@regionh.dk. 7. Department of Gynaecology and Obstetrics, Nordsjællands Hospital Hillerød, Dyrehavevej 29, 3400 Hillerød, Denmark. Electronic address: ellen.christine.leth.loekkegaard@regionh.dk. 8. Department of Gynaecology and Obstetrics, Nordsjællands Hospital Hillerød, Dyrehavevej 29, 3400 Hillerød, Denmark. Electronic address: paul.vignir.axelsson.bryde@regionh.dk.
Abstract
OBJECTIVE: To gain insight into pregnant women's preferences if given a choice between getting antibiotic prophylaxis before or after cord clamping during caesarean delivery. STUDY DESIGN: A qualitative semi-structured interview-study. The interviews were conducted at a Danish Hospital, with about 4000 deliveries a year. Fourteen individual semi-structured interviews were conducted with pregnant women, either considering or having a planned caesarean section, or scheduled for induction due to post-term gestational age. A systematic text condensation approach was used to analyze the transcribed interviews. RESULTS: Ten of the fourteen women favored antibiotic administration after cord clamping. Despite any adverse effects to the infant's microbiota and increased risk of long-term health outcomes were only hypothetical and the risk reduction in postpartum infections being well documented, they did not want to expose their offspring to antibiotics. Those who preferred antibiotic prophylaxis before cord clamping were concerned, if they would be able to care for the infant in case of a maternal infection. Three of the women preferring antibiotics after cord clamping said they would potentially change preference, if the maternal risk was higher. Most women preferred to be informed of the use of prophylactic antibiotic and that the timing has consequences for trans-placental exposure to the infant. CONCLUSIONS: With most of the interviewed women preferring antibiotic administration after cord clamping, we suggest patients should be involved in the decision regarding timing of prophylactic antibiotics before caesarean section.
OBJECTIVE: To gain insight into pregnant women's preferences if given a choice between getting antibiotic prophylaxis before or after cord clamping during caesarean delivery. STUDY DESIGN: A qualitative semi-structured interview-study. The interviews were conducted at a Danish Hospital, with about 4000 deliveries a year. Fourteen individual semi-structured interviews were conducted with pregnant women, either considering or having a planned caesarean section, or scheduled for induction due to post-term gestational age. A systematic text condensation approach was used to analyze the transcribed interviews. RESULTS: Ten of the fourteen women favored antibiotic administration after cord clamping. Despite any adverse effects to the infant's microbiota and increased risk of long-term health outcomes were only hypothetical and the risk reduction in postpartum infections being well documented, they did not want to expose their offspring to antibiotics. Those who preferred antibiotic prophylaxis before cord clamping were concerned, if they would be able to care for the infant in case of a maternal infection. Three of the women preferring antibiotics after cord clamping said they would potentially change preference, if the maternal risk was higher. Most women preferred to be informed of the use of prophylactic antibiotic and that the timing has consequences for trans-placental exposure to the infant. CONCLUSIONS: With most of the interviewed women preferring antibiotic administration after cord clamping, we suggest patients should be involved in the decision regarding timing of prophylactic antibiotics before caesarean section.
Authors: Katherine E Eddy; Rana Islamiah Zahroh; Meghan A Bohren; Mercedes Bonet; Caroline S E Homer; Joshua P Vogel Journal: PLoS One Date: 2022-09-01 Impact factor: 3.752