Bruna Cunha Mendes1, Cândice Laís Knöner Copetti2, Vilma Simões Pereira Panza2, Lucas B R Orssatto3, Julia Salvan da Rosa4, Fernando Diefenthaeler5, Eduardo Monguilhott Dalmarco4, Patricia Faria Di Pietro2, Débora Kurrle Rieger2. 1. Nutrition Postgraduate Program, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil. Electronic address: bruna.mendes@posgrad.ufsc.br. 2. Nutrition Postgraduate Program, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil. 3. School of Exercise and Nutrition Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Australia. 4. Pharmacy Postgraduate Program, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil. 5. Physical Education Postgraduate Program, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil.
Abstract
OBJECTIVE: High-intensity intermittent exercise (HIIE) may enhance the antiinflammatory status. The juçara fruit juice (JFJ) has well-established antioxidant and antiinflammatory properties. This study investigated the effect of JFJ consumption on the inflammatory response to HIIE in physically active subjects. METHODS: In a randomized crossover design, 15 men were assigned to drink 250 mL of either JFJ or water (control) 1 h before a cycling HIIE session (seven sets of 60 s at 100% peak power output; 75 s recovery between sets). Blood samples were obtained before and at 0, 30, and 60 min post-HIIE, and the serum was analyzed for interleukin (IL)-6, IL-1β, IL-8, IL-10, tumor necrosis factor-α, and cortisol. RESULTS: After HIIE, the IL-6 levels were higher than baseline (percent change) at 30 min (P = 0.041) and 60 min (P = 0.038) for the control, but were unaffected by JFJ. IL-10 was higher in the JFJ group than in the control at 30 min (d = ‒0.63). Tumor necrosis factor-α was lower than baseline at 30 min for the control (d = ‒0.71) and at 60 min for the JFJ group (d = ‒0.60). For control, cortisol increased to higher than the baseline at 30 and 60 min (d = 0.54 and d = 0.76, respectively). For the JFJ group, the cortisol levels were significantly higher than the baseline at 30 min (P = 0.022). Performance during sprints was higher in the JFJ group than in the control (P = 0.002). In the control group, performance was with both IL-6 (semipartial correlation; sr = -0.59, large effect size) and cortisol at 0 h (sr = -0.52, large effect size). CONCLUSIONS: JFJ intake attenuated the antiinflammatory response to HIIE, possibly resulting from a lower degree of muscle stress.
OBJECTIVE: High-intensity intermittent exercise (HIIE) may enhance the antiinflammatory status. The juçara fruit juice (JFJ) has well-established antioxidant and antiinflammatory properties. This study investigated the effect of JFJ consumption on the inflammatory response to HIIE in physically active subjects. METHODS: In a randomized crossover design, 15 men were assigned to drink 250 mL of either JFJ or water (control) 1 h before a cycling HIIE session (seven sets of 60 s at 100% peak power output; 75 s recovery between sets). Blood samples were obtained before and at 0, 30, and 60 min post-HIIE, and the serum was analyzed for interleukin (IL)-6, IL-1β, IL-8, IL-10, tumor necrosis factor-α, and cortisol. RESULTS: After HIIE, the IL-6 levels were higher than baseline (percent change) at 30 min (P = 0.041) and 60 min (P = 0.038) for the control, but were unaffected by JFJ. IL-10 was higher in the JFJ group than in the control at 30 min (d = ‒0.63). Tumor necrosis factor-α was lower than baseline at 30 min for the control (d = ‒0.71) and at 60 min for the JFJ group (d = ‒0.60). For control, cortisol increased to higher than the baseline at 30 and 60 min (d = 0.54 and d = 0.76, respectively). For the JFJ group, the cortisol levels were significantly higher than the baseline at 30 min (P = 0.022). Performance during sprints was higher in the JFJ group than in the control (P = 0.002). In the control group, performance was with both IL-6 (semipartial correlation; sr = -0.59, large effect size) and cortisol at 0 h (sr = -0.52, large effect size). CONCLUSIONS: JFJ intake attenuated the antiinflammatory response to HIIE, possibly resulting from a lower degree of muscle stress.
Authors: Cândice L K Copetti; Fernando Diefenthaeler; Fernanda Hansen; Francilene G K Vieira; Patricia F Di Pietro Journal: Antioxidants (Basel) Date: 2022-02-15