Literature DB >> 34273069

Undiagnosed Hyperglycemia Is a Potential Long-term Risk in Metabolic Surgery Patients: 7 Years Follow-up Study.

Amrit Manik Nasta1, Ramen Goel2, Madhu Goel3, Amenah Malek3.   

Abstract

INTRODUCTION: Diabetes is considered to be a surgically correctable illness. As glycemic control begins soon after surgery, the cessation of anti-diabetic medications is early. Patients believe that their diabetes has been "cured" and the need for blood sugar monitoring is forgotten, leading to undiagnosed hyperglycemia and risk of diabetes-related complications. AIMS: To study the effect of bariatric surgery on long-term glycemic control and identify the patients with undiagnosed hyperglycemia.
METHODS: All patients with type 2 diabetes who underwent bariatric surgery at our center from January 2012 to December 2013 were included in the study. For each patient, demographic, preoperative, and postoperative data were retrospectively reviewed.
RESULTS: Out of the total 119 patients with diabetes, 91 patients underwent sleeve gastrectomy and 28 underwent Roux-en-Y gastric bypass. Diabetes status at 7 years of follow-up was possible in 53 (44.5%) patients: 44 (48.4%) in SG and 9 (32.2%) in RYGB groups. Overall, complete remission at 7 years was seen in 17 (32.1%) patients and partial remission in 12 (22.6%) patients. Amongst non-remitters (n = 24, 45.3%), 7 (13.2%) patients were on medications with good glycemic control (A1C < 6.5) while 8 (15.1%) patients had poor control (A1C > 6.5) despite ongoing medications. Additionally, 9 (17%) patients had poor glycemic control (A1C > 6.5) and were not receiving any anti-diabetic medications. Patients in whom follow-up A1C was unavailable and their diabetes status remain unknown were 66 (55.5%) at 7 years.
CONCLUSION: Our study clearly demonstrates high risk of undiagnosed hyperglycemia. Regular long-term follow-up in diabetic patients is even more desirable than amongst patients undergoing bariatric surgery for weight loss alone. Graphical abstract.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Bariatric surgery; Complications; Diabetes; Long term; Metabolic surgery; Relapse; Remission; Uncontrolled hyperglycemia

Mesh:

Year:  2021        PMID: 34273069     DOI: 10.1007/s11695-021-05570-z

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  10 in total

Review 1.  Long-term and midterm outcomes of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass: a systematic review and meta-analysis of comparative studies.

Authors:  Saeed Shoar; Alan A Saber
Journal:  Surg Obes Relat Dis       Date:  2016-08-18       Impact factor: 4.734

2.  IFSO-APC consensus statements 2011.

Authors:  Kazunori Kasama; Wilfred Mui; Wei Jei Lee; Muffazal Lakdawala; Takeshi Naitoh; Yosuke Seki; Akira Sasaki; Go Wakabayashi; Iwao Sasaki; Isao Kawamura; Lilian Kow; Harry Frydenberg; Anton Chen; Mahendra Narwaria; Pradeep Chowbey
Journal:  Obes Surg       Date:  2012-05       Impact factor: 4.129

3.  Systematic Review and Meta-Analysis of Randomised Controlled Trials Comparing Long-Term Outcomes of Roux-En-Y Gastric Bypass and Sleeve Gastrectomy.

Authors:  Alistair J Sharples; Kamal Mahawar
Journal:  Obes Surg       Date:  2020-02       Impact factor: 4.129

4.  Long-term follow-up after bariatric surgery in a national cohort.

Authors:  J Thereaux; T Lesuffleur; M Païta; S Czernichow; A Basdevant; S Msika; B Millat; A Fagot-Campagna
Journal:  Br J Surg       Date:  2017-06-28       Impact factor: 6.939

5.  Individualized Metabolic Surgery Score: Procedure Selection Based on Diabetes Severity.

Authors:  Ali Aminian; Stacy A Brethauer; Amin Andalib; Amy S Nowacki; Amanda Jimenez; Ricard Corcelles; Zubaidah Nor Hanipah; Suriya Punchai; Deepak L Bhatt; Sangeeta R Kashyap; Bartolome Burguera; Antonio M Lacy; Josep Vidal; Philip R Schauer
Journal:  Ann Surg       Date:  2017-10       Impact factor: 12.969

6.  How do we define cure of diabetes?

Authors:  John B Buse; Sonia Caprio; William T Cefalu; Antonio Ceriello; Stefano Del Prato; Silvio E Inzucchi; Sue McLaughlin; Gordon L Phillips; R Paul Robertson; Francesco Rubino; Richard Kahn; M Sue Kirkman
Journal:  Diabetes Care       Date:  2009-11       Impact factor: 19.112

7.  Comparative analysis of weight loss and resolution of comorbidities between laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass: A systematic review and meta-analysis based on 18 studies.

Authors:  Youkui Han; Yang Jia; Honglei Wang; Lei Cao; Yongjie Zhao
Journal:  Int J Surg       Date:  2020-03-06       Impact factor: 6.071

Review 8.  Minireview: Hormonal and metabolic mechanisms of diabetes remission after gastrointestinal surgery.

Authors:  Joshua P Thaler; David E Cummings
Journal:  Endocrinology       Date:  2009-04-16       Impact factor: 4.736

9.  Association of bariatric surgery with long-term remission of type 2 diabetes and with microvascular and macrovascular complications.

Authors:  Lars Sjöström; Markku Peltonen; Peter Jacobson; Sofie Ahlin; Johanna Andersson-Assarsson; Åsa Anveden; Claude Bouchard; Björn Carlsson; Kristjan Karason; Hans Lönroth; Ingmar Näslund; Elisabeth Sjöström; Magdalena Taube; Hans Wedel; Per-Arne Svensson; Kajsa Sjöholm; Lena M S Carlsson
Journal:  JAMA       Date:  2014-06-11       Impact factor: 56.272

10.  Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss at 5 Years Among Patients With Morbid Obesity: The SLEEVEPASS Randomized Clinical Trial.

Authors:  Paulina Salminen; Mika Helmiö; Jari Ovaska; Anne Juuti; Marja Leivonen; Pipsa Peromaa-Haavisto; Saija Hurme; Minna Soinio; Pirjo Nuutila; Mikael Victorzon
Journal:  JAMA       Date:  2018-01-16       Impact factor: 56.272

  10 in total

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