| Literature DB >> 34272762 |
Georges El Hasbani1, Ali T Taher1, Ali S M Jawad2, Imad Uthman1.
Abstract
Whether affecting children or adults, SARS-CoV-2 infection (COVID-19) can have multi-organ involvement mediated by an inflammatory cascade. Immunoglobulin A (IgA) is one of the key components of the inflammatory cascade that can lead to endothelial injury and inflammation. IgA vasculitis or Henoch-Schönlein purpura (HSP) has been rarely reported in the context of COVID-19. In this report, we highlight a case of HSP occurring 2 days after diagnosis of COVID-19 in a 16-year-old boy, who presented with palpable purpura of the lower extremities and buttocks, diffuse abdominal pain, hemoptysis, and hematochezia. He was treated with oral prednisolone with rapid clinical improvement.Entities:
Keywords: COVID-19; Henoch-Schönlein purpura; immunomodulation; vasculitides
Year: 2021 PMID: 34272762 DOI: 10.1111/pde.14699
Source DB: PubMed Journal: Pediatr Dermatol ISSN: 0736-8046 Impact factor: 1.588