Matthew R Test1, Rita Mangione-Smith2,3, Chuan Zhou2,3, Davene R Wright2,3, Elizabeth E Halvorson4, David P Johnson5, Derek J Williams5, Joyee G Vachani6, Talia A Hitt7, Joel S Tieder2. 1. Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Washington matthew.test@seattlechildrens.org. 2. Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Washington. 3. Seattle Children's Research Institute, Seattle, Washington. 4. Department of Pediatrics, School of Medicine, Wake Forest University, Winston-Salem, North Carolina. 5. Division of Hospital Medicine, Department of Pediatrics, Monroe Carell Jr Children's Hospital at Vanderbilt and School of Medicine, Vanderbilt University, Nashville, Tennessee. 6. Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas. 7. Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Abstract
OBJECTIVES: Obesity has rapidly become a major problem for children that has adverse effects on respiratory health. We sought to assess the impact of obesity on health-related quality of life (HRQOL) and hospital outcomes for children hospitalized with asthma or pneumonia. METHODS: In this multicenter prospective cohort study, we evaluated children (aged 2-16 years) hospitalized with an acute asthma exacerbation or pneumonia between July 1, 2014, and June 30, 2016. Subjects or their family completed surveys for child HRQOL (PedsQL Physical Functioning and Psychosocial Functioning Scales, with scores ranging from 0 to 100) on hospital presentation and 2-6 weeks after discharge. BMI categories were defined as normal weight, overweight, and obesity on the basis of BMI percentiles for age and sex per national guidelines. Multivariable regression models were used to examine associations between BMI category and HRQOL, length of stay, and 30-day reuse. RESULTS: Among 716 children, 82 (11.4%) were classified as having overweight and 138 (19.3%) as having obesity. For children hospitalized with asthma or pneumonia, obesity was not associated with worse HRQOL at presentation or 2-6 weeks after discharge, hospital length of stay, or 30-day reuse. CONCLUSIONS: Nearly 1 in 3 children seen in the hospital for an acute asthma exacerbation or pneumonia had overweight or obesity; however, among the population of children in our study, obesity alone does not appear to be associated with worse HRQOL or hospital outcomes.
OBJECTIVES: Obesity has rapidly become a major problem for children that has adverse effects on respiratory health. We sought to assess the impact of obesity on health-related quality of life (HRQOL) and hospital outcomes for children hospitalized with asthma or pneumonia. METHODS: In this multicenter prospective cohort study, we evaluated children (aged 2-16 years) hospitalized with an acute asthma exacerbation or pneumonia between July 1, 2014, and June 30, 2016. Subjects or their family completed surveys for child HRQOL (PedsQL Physical Functioning and Psychosocial Functioning Scales, with scores ranging from 0 to 100) on hospital presentation and 2-6 weeks after discharge. BMI categories were defined as normal weight, overweight, and obesity on the basis of BMI percentiles for age and sex per national guidelines. Multivariable regression models were used to examine associations between BMI category and HRQOL, length of stay, and 30-day reuse. RESULTS: Among 716 children, 82 (11.4%) were classified as having overweight and 138 (19.3%) as having obesity. For children hospitalized with asthma or pneumonia, obesity was not associated with worse HRQOL at presentation or 2-6 weeks after discharge, hospital length of stay, or 30-day reuse. CONCLUSIONS: Nearly 1 in 3 children seen in the hospital for an acute asthma exacerbation or pneumonia had overweight or obesity; however, among the population of children in our study, obesity alone does not appear to be associated with worse HRQOL or hospital outcomes.
Authors: Anna M Bramley; Carrie Reed; Lyn Finelli; Wesley H Self; Krow Ampofo; Sandra R Arnold; Derek J Williams; Carlos G Grijalva; Evan J Anderson; Chris Stockmann; Christopher Trabue; Sherene Fakhran; Robert Balk; Jonathan A McCullers; Andrew T Pavia; Kathryn M Edwards; Richard G Wunderink; Seema Jain Journal: J Infect Dis Date: 2017-06-15 Impact factor: 5.226
Authors: Jessica Bettenhausen; Henry Puls; Mary Ann Queen; Christina Peacock; Stephanie Burrus; Christopher Miller; Ashley Daly; Jeffrey D Colvin Journal: J Hosp Med Date: 2014-12-02 Impact factor: 2.960
Authors: R J Kuczmarski; C L Ogden; L M Grummer-Strawn; K M Flegal; S S Guo; R Wei; Z Mei; L R Curtin; A F Roche; C L Johnson Journal: Adv Data Date: 2000-06-08
Authors: Tamara D Simon; Mary Lawrence Cawthon; Susan Stanford; Jean Popalisky; Dorothy Lyons; Peter Woodcox; Margaret Hood; Alex Y Chen; Rita Mangione-Smith Journal: Pediatrics Date: 2014-05-12 Impact factor: 7.124
Authors: Teumzghi F Mebrahtu; Richard G Feltbower; Darren C Greenwood; Roger C Parslow Journal: Pediatr Allergy Immunol Date: 2015-01-19 Impact factor: 6.377