Nguyen Hai Nam1,2,3, Phan Thi My Tien3,4, Le Van Truong3,5, Toka Aziz El-Ramly3,6, Pham Gia Anh3,4, Nguyen Thi Hien3,7, El Marabea Mahmoud3,8, Mennatullah Mohamed Eltaras3,9, Sarah Abd Elaziz Khader3,10, Mohammed Salah Desokey3,11, Ramy Magdy Gayed3,12, Shamael Thabit Mohammed Alhady3,13, Bao-Tran Do Le3,14, Do Phuc Nhu Nguyen3,15, Ranjit Tiwari3,16, Mohammed Eldoadoa3,17, Britney Howard3,18, Tran Thanh Trung3, Nguyen Tien Huy19. 1. Graduate School of Medicine, Kyoto University, Kyoto, Japan. 2. Harvard Medical School, Global Clinical Scholars Research Training Program, Boston, Massachusetts, United States of America. 3. Online Research Club, Nagasaki, Japan. 4. University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. 5. Traditional Medicine Hospital of Ministry of Public Security, Hanoi, Vietnam. 6. Faculty of Medicine, University of Alexandria, Alexandria, Egypt. 7. Emergency Department, Hue City hospital, Hue City, Vietnam. 8. Faculty of Medicine, Tanta University, Tanta, Egypt. 9. Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt. 10. Faculty of Medicine, Ain Shams University, Cairo, Egypt. 11. Faculty of Medicine, Aswan University, Aswan, Egypt. 12. Faculty of Medicine, Cairo university, Cairo, Egypt. 13. Faculty of Medicine, University of Gezira, Wad Medani, Sudan. 14. University of California, Los Angeles, Los Angeles, California, United States of America. 15. Epidemiology Department, Institute of Public Health Ho Chi Minh City, Ho Chi Minh City, Vietnam. 16. Faculty of Medicine, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal. 17. Milton Keynes University Hospital, Milton Keynes, United Kingdom. 18. American University of the Caribbean School of Medicine, Cupecoy, Sint Maarten. 19. School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Abstract
BACKGROUND: In response to the spread of the coronavirus disease 2019 (COVID-19), plenty of control measures were proposed. To assess the impact of current control measures on the number of new case indices 14 countries with the highest confirmed cases, highest mortality rate, and having a close relationship with the outbreak's origin; were selected and analyzed. METHODS: In the study, we analyzed the impact of five control measures, including centralized isolation of all confirmed cases, closure of schools, closure of public areas, closure of cities, and closure of borders of the 14 targeted countries according to their timing; by comparing its absolute effect average, its absolute effect cumulative, and its relative effect average. RESULTS: Our analysis determined that early centralized isolation of all confirmed cases was represented as a core intervention in significantly disrupting the pandemic's spread. This strategy helped in successfully controlling the early stage of the outbreak when the total number of cases were under 100, without the requirement of the closure of cities and public areas, which would impose a negative impact on the society and its economy. However, when the number of cases increased with the apparition of new clusters, coordination between centralized isolation and non-pharmaceutical interventions facilitated control of the crisis efficiently. CONCLUSION: Early centralized isolation of all confirmed cases should be implemented at the time of the first detected infectious case.
BACKGROUND: In response to the spread of the coronavirus disease 2019 (COVID-19), plenty of control measures were proposed. To assess the impact of current control measures on the number of new case indices 14 countries with the highest confirmed cases, highest mortality rate, and having a close relationship with the outbreak's origin; were selected and analyzed. METHODS: In the study, we analyzed the impact of five control measures, including centralized isolation of all confirmed cases, closure of schools, closure of public areas, closure of cities, and closure of borders of the 14 targeted countries according to their timing; by comparing its absolute effect average, its absolute effect cumulative, and its relative effect average. RESULTS: Our analysis determined that early centralized isolation of all confirmed cases was represented as a core intervention in significantly disrupting the pandemic's spread. This strategy helped in successfully controlling the early stage of the outbreak when the total number of cases were under 100, without the requirement of the closure of cities and public areas, which would impose a negative impact on the society and its economy. However, when the number of cases increased with the apparition of new clusters, coordination between centralized isolation and non-pharmaceutical interventions facilitated control of the crisis efficiently. CONCLUSION: Early centralized isolation of all confirmed cases should be implemented at the time of the first detected infectious case.
Authors: Qun Li; Xuhua Guan; Peng Wu; Xiaoye Wang; Lei Zhou; Yeqing Tong; Ruiqi Ren; Kathy S M Leung; Eric H Y Lau; Jessica Y Wong; Xuesen Xing; Nijuan Xiang; Yang Wu; Chao Li; Qi Chen; Dan Li; Tian Liu; Jing Zhao; Man Liu; Wenxiao Tu; Chuding Chen; Lianmei Jin; Rui Yang; Qi Wang; Suhua Zhou; Rui Wang; Hui Liu; Yinbo Luo; Yuan Liu; Ge Shao; Huan Li; Zhongfa Tao; Yang Yang; Zhiqiang Deng; Boxi Liu; Zhitao Ma; Yanping Zhang; Guoqing Shi; Tommy T Y Lam; Joseph T Wu; George F Gao; Benjamin J Cowling; Bo Yang; Gabriel M Leung; Zijian Feng Journal: N Engl J Med Date: 2020-01-29 Impact factor: 176.079
Authors: Marina Borro; Paolo Di Girolamo; Giovanna Gentile; Ottavia De Luca; Robert Preissner; Adriano Marcolongo; Stefano Ferracuti; Maurizio Simmaco Journal: Int J Environ Res Public Health Date: 2020-08-02 Impact factor: 3.390
Authors: Eman A Toraih; Mohammad H Hussein; Rami M Elshazli; Manal S Fawzy; August Houghton; Danielle Tatum; Mary Killackey; Emad Kandil; Juan Duchesne Journal: Ann Surg Date: 2021-01-01 Impact factor: 13.787