BACKGROUND: Approximately 30-40% of pancreatoduodenectomies for adenocarcinomas result in nonpancreatic periampullary adenocarcinoma as the final diagnosis. Depending on the origin, a distinction is made between four different carcinomas with histomorphological subtypes. OBJECTIVE: Carcinoma location and subtype are of prognostic and therapeutic relevance; however, the preoperative differentiation is often incorrect despite modern diagnostics. MATERIAL AND METHODS: Overview of the current literature on the classification and preoperative diagnostics of periampullary adenocarcinomas. RESULTS: A precise knowledge of the papillary anatomy is necessary for the correct classification of diagnostic findings. Current studies demonstrate diagnostically valuable information from the anamnesis, imaging and endoscopy. CONCLUSION: In ca. 70-80% of cases a correct diagnosis of the type of periampullary adenocarcinoma is possible on the basis of interdisciplinary diagnostics. This potentially enables a correspondingly individualized treatment planning in the preoperative phase.
BACKGROUND: Approximately 30-40% of pancreatoduodenectomies for adenocarcinomas result in nonpancreatic periampullary adenocarcinoma as the final diagnosis. Depending on the origin, a distinction is made between four different carcinomas with histomorphological subtypes. OBJECTIVE: Carcinoma location and subtype are of prognostic and therapeutic relevance; however, the preoperative differentiation is often incorrect despite modern diagnostics. MATERIAL AND METHODS: Overview of the current literature on the classification and preoperative diagnostics of periampullary adenocarcinomas. RESULTS: A precise knowledge of the papillary anatomy is necessary for the correct classification of diagnostic findings. Current studies demonstrate diagnostically valuable information from the anamnesis, imaging and endoscopy. CONCLUSION: In ca. 70-80% of cases a correct diagnosis of the type of periampullary adenocarcinoma is possible on the basis of interdisciplinary diagnostics. This potentially enables a correspondingly individualized treatment planning in the preoperative phase.
Authors: René Adam; Laurence Chiche; Thomas Aloia; Dominique Elias; Rémy Salmon; Michel Rivoire; Daniel Jaeck; Jean Saric; Yves Patrice Le Treut; Jacques Belghiti; Georges Mantion; Gilles Mentha Journal: Ann Surg Date: 2006-10 Impact factor: 12.969
Authors: Mechteld C de Jong; Susan Tsai; John L Cameron; Christopher L Wolfgang; Kenzo Hirose; Mark G van Vledder; Frederic Eckhauser; Joseph M Herman; Barish H Edil; Michael A Choti; Richard D Schulick; Timothy M Pawlik Journal: J Surg Oncol Date: 2010-09-01 Impact factor: 3.454
Authors: Shuji Isaji; Shugo Mizuno; John A Windsor; Claudio Bassi; Carlos Fernández-Del Castillo; Thilo Hackert; Aoi Hayasaki; Matthew H G Katz; Sun-Whe Kim; Masashi Kishiwada; Hirohisa Kitagawa; Christoph W Michalski; Christopher L Wolfgang Journal: Pancreatology Date: 2017-11-22 Impact factor: 3.996
Authors: Maximilian Bockhorn; Faik G Uzunoglu; Mustapha Adham; Clem Imrie; Miroslav Milicevic; Aken A Sandberg; Horacio J Asbun; Claudio Bassi; Markus Büchler; Richard M Charnley; Kevin Conlon; Laureano Fernandez Cruz; Christos Dervenis; Abe Fingerhutt; Helmut Friess; Dirk J Gouma; Werner Hartwig; Keith D Lillemoe; Marco Montorsi; John P Neoptolemos; Shailesh V Shrikhande; Kyoichi Takaori; William Traverso; Yogesh K Vashist; Charles Vollmer; Charles J Yeo; Jakob R Izbicki Journal: Surgery Date: 2014-02-07 Impact factor: 3.982
Authors: Peter Bronsert; Ilona Kohler; Martin Werner; Frank Makowiec; Simon Kuesters; Jens Hoeppner; Ulrich Theodor Hopt; Tobias Keck; Dirk Bausch; Ulrich Friedrich Wellner Journal: BMC Cancer Date: 2013-09-22 Impact factor: 4.430
Authors: Horacio J Asbun; Kevin Conlon; Laureano Fernandez-Cruz; Helmut Friess; Shailesh V Shrikhande; Mustapha Adham; Claudio Bassi; Maximilian Bockhorn; Markus Büchler; Richard M Charnley; Christos Dervenis; Abe Fingerhutt; Dirk J Gouma; Werner Hartwig; Clem Imrie; Jakob R Izbicki; Keith D Lillemoe; Miroslav Milicevic; Marco Montorsi; John P Neoptolemos; Aken A Sandberg; Michael Sarr; Charles Vollmer; Charles J Yeo; L William Traverso Journal: Surgery Date: 2014-01-02 Impact factor: 3.982