Literature DB >> 34264313

DRP1: a novel regulator of PCSK9 secretion and degradation.

Sean A Burnap1, Manuel Mayr1.   

Abstract

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Year:  2021        PMID： 34264313      PMCID： PMC8479798          DOI： 10.1093/cvr/cvab227

Source DB:  PubMed          Journal:  Cardiovasc Res        ISSN： 0008-6363            Impact factor:   13.081


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  12 in total

1.  Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.

Authors:  Jonathan C Cohen; Eric Boerwinkle; Thomas H Mosley; Helen H Hobbs
Journal:  N Engl J Med       Date:  2006-03-23       Impact factor: 91.245

2.  GRP94 Regulates Circulating Cholesterol Levels through Blockade of PCSK9-Induced LDLR Degradation.

Authors:  Steve Poirier; Maya Mamarbachi; Wan-Ting Chen; Amy S Lee; Gaetan Mayer
Journal:  Cell Rep       Date:  2015-11-25       Impact factor: 9.423

3.  Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury.

Authors:  Danchen Wu; Asish Dasgupta; Kuang-Hueih Chen; Monica Neuber-Hess; Jignesh Patel; Timothy E Hurst; Jeffrey D Mewburn; Patricia D A Lima; Elahe Alizadeh; Ashley Martin; Michael Wells; Victor Snieckus; Stephen L Archer
Journal:  FASEB J       Date:  2019-12-02       Impact factor: 5.191

4.  The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species.

Authors:  Evan A Bordt; Pascaline Clerc; Brian A Roelofs; Andrew J Saladino; László Tretter; Vera Adam-Vizi; Edward Cherok; Ahmed Khalil; Nagendra Yadava; Shealinna X Ge; T Chase Francis; Nolan W Kennedy; Lora K Picton; Tanya Kumar; Sruti Uppuluri; Alexandrea M Miller; Kie Itoh; Mariusz Karbowski; Hiromi Sesaki; R Blake Hill; Brian M Polster
Journal:  Dev Cell       Date:  2017-03-27       Impact factor: 12.270

5.  Dynamin-Related Protein 1 Inhibition Attenuates Cardiovascular Calcification in the Presence of Oxidative Stress.

Authors:  Maximillian A Rogers; Natalia Maldonado; Joshua D Hutcheson; Claudia Goettsch; Shinji Goto; Iwao Yamada; Tyler Faits; Hiromi Sesaki; Masanori Aikawa; Elena Aikawa
Journal:  Circ Res       Date:  2017-06-12       Impact factor: 17.367

6.  The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury.

Authors:  Paul F Lebeau; Hanny Wassef; Jae Hyun Byun; Khrystyna Platko; Brandon Ason; Simon Jackson; Joshua Dobroff; Susan Shetterly; William G Richards; Ali A Al-Hashimi; Kevin Doyoon Won; Majambu Mbikay; Annik Prat; An Tang; Guillaume Paré; Renata Pasqualini; Nabil G Seidah; Wadih Arap; Michel Chrétien; Richard C Austin
Journal:  J Clin Invest       Date:  2021-01-19       Impact factor: 14.808

7.  Disruption of mitochondrial fission in the liver protects mice from diet-induced obesity and metabolic deterioration.

Authors:  Lixiang Wang; Takaya Ishihara; Yuta Ibayashi; Keita Tatsushima; Daiki Setoyama; Yuki Hanada; Yukina Takeichi; Shohei Sakamoto; Sadaki Yokota; Katsuyoshi Mihara; Dongchon Kang; Naotada Ishihara; Ryoichi Takayanagi; Masatoshi Nomura
Journal:  Diabetologia       Date:  2015-08-02       Impact factor: 10.122

8.  An oral antisense oligonucleotide for PCSK9 inhibition.

Authors:  Peter Gennemark; Katrin Walter; Niclas Clemmensen; Dinko Rekić; Catarina A M Nilsson; Jane Knöchel; Mikko Hölttä; Linda Wernevik; Birgitta Rosengren; Dorota Kakol-Palm; Yanfeng Wang; Rosie Z Yu; Richard S Geary; Stan J Riney; Brett P Monia; Rikard Isaksson; Rasmus Jansson-Löfmark; Cristina S J Rocha; Daniel Lindén; Eva Hurt-Camejo; Rosanne Crooke; Lloyd Tillman; Tina Rydén-Bergsten; Björn Carlsson; Ulf Andersson; Marie Elebring; Anna Tivesten; Nigel Davies
Journal:  Sci Transl Med       Date:  2021-05-12       Impact factor: 17.956

9.  Dynamin-related protein 1 inhibition reduces hepatic PCSK9 secretion.

Authors:  Maximillian A Rogers; Joshua D Hutcheson; Takehito Okui; Claudia Goettsch; Sasha A Singh; Arda Halu; Florian Schlotter; Hideyuki Higashi; Lixiang Wang; Mary C Whelan; Andrew K Mlynarchik; Alan Daugherty; Masatoshi Nomura; Masanori Aikawa; Elena Aikawa
Journal:  Cardiovasc Res       Date:  2021-09-28       Impact factor: 10.787

10.  In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.

Authors:  Kiran Musunuru; Alexandra C Chadwick; Taiji Mizoguchi; Sara P Garcia; Jamie E DeNizio; Caroline W Reiss; Kui Wang; Sowmya Iyer; Chaitali Dutta; Victoria Clendaniel; Michael Amaonye; Aaron Beach; Kathleen Berth; Souvik Biswas; Maurine C Braun; Huei-Mei Chen; Thomas V Colace; John D Ganey; Soumyashree A Gangopadhyay; Ryan Garrity; Lisa N Kasiewicz; Jennifer Lavoie; James A Madsen; Yuri Matsumoto; Anne Marie Mazzola; Yusuf S Nasrullah; Joseph Nneji; Huilan Ren; Athul Sanjeev; Madeleine Shay; Mary R Stahley; Steven H Y Fan; Ying K Tam; Nicole M Gaudelli; Giuseppe Ciaramella; Leslie E Stolz; Padma Malyala; Christopher J Cheng; Kallanthottathil G Rajeev; Ellen Rohde; Andrew M Bellinger; Sekar Kathiresan
Journal:  Nature       Date:  2021-05-19       Impact factor: 69.504
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