Juan Gros-Otero1,2, Samira Ketabi3, Rafael Cañones-Zafra3, Montserrat Garcia-Gonzalez4,5, Cesar Villa-Collar5,6, Santiago Casado7,8, Miguel A Teus3,5. 1. Clínica Rementería, Calle Almagro, 36, Madrid, Spain. juangros@gmail.com. 2. Universidad CEU San Pablo, Campus Montepríncipe, Madrid, Spain. juangros@gmail.com. 3. Hospital Universitario Príncipe de Asturias, Carretera Meco s/n, Madrid, Spain. 4. Clínica Rementería, Calle Almagro, 36, Madrid, Spain. 5. Clínica Novovisión, Paseo de la Castellan, Madrid, Spain. 6. Universidad Europea, Madrid, Spain. 7. Facultad de Ciencia e Ingeniería de Alimentos, Universidad Técnica de Ambato, Ambato, Ecuador. 8. IMDEA-Nanociencia, Campus Universitario de Cantoblanco, 28049, Madrid, Spain.
Abstract
BACKGROUND: To compare the anterior surface roughness of two commercially available posterior chamber phakic intraocular lenses (IOLs) using atomic force microscopy (AFM). METHODS: Four phakic IOLs were used for this prospective, experimental study: two Visian ICL EVO+ V5 lenses and two iPCL 2.0 lenses. All of them were brand new, were not previously implanted in humans, were monofocal and had a dioptric power of - 12 diopters (D). The anterior surface roughness was assessed using a JPK NanoWizard II® atomic force microscope in contact mode immersed in liquid. Olympus OMCL-RC800PSA commercial silicon nitride cantilever tips were used. Anterior surface roughness measurements were made in 7 areas of 10 × 10 μm at 512 × 512 point resolution. The roughness was measured using the root-mean-square (RMS) value within the given regions. RESULTS: The mean of all anterior surface roughness measurements was 6.09 ± 1.33 nm (nm) in the Visian ICL EVO+ V5 and 3.49 ± 0.41 nm in the iPCL 2.0 (p = 0.001). CONCLUSION: In the current study, we found a statistically significant smoother anterior surface in the iPCL 2.0 phakic intraocular lenses compared with the VISIAN ICL EVO+ V5 lenses when studied with atomic force microscopy.
BACKGROUND: To compare the anterior surface roughness of two commercially available posterior chamber phakic intraocular lenses (IOLs) using atomic force microscopy (AFM). METHODS: Four phakic IOLs were used for this prospective, experimental study: two Visian ICL EVO+ V5 lenses and two iPCL 2.0 lenses. All of them were brand new, were not previously implanted in humans, were monofocal and had a dioptric power of - 12 diopters (D). The anterior surface roughness was assessed using a JPK NanoWizard II® atomic force microscope in contact mode immersed in liquid. Olympus OMCL-RC800PSA commercial silicon nitride cantilever tips were used. Anterior surface roughness measurements were made in 7 areas of 10 × 10 μm at 512 × 512 point resolution. The roughness was measured using the root-mean-square (RMS) value within the given regions. RESULTS: The mean of all anterior surface roughness measurements was 6.09 ± 1.33 nm (nm) in the Visian ICL EVO+ V5 and 3.49 ± 0.41 nm in the iPCL 2.0 (p = 0.001). CONCLUSION: In the current study, we found a statistically significant smoother anterior surface in the iPCL 2.0 phakic intraocular lenses compared with the VISIAN ICL EVO+ V5 lenses when studied with atomic force microscopy.
Authors: Juan Gros-Otero; Samira Ketabi; Rafael Cañones-Zafra; Montserrat Garcia-Gonzalez; Alberto Parafita-Fernandez; Cesar Villa-Collar; Santiago Casado; Miguel Teus Journal: Graefes Arch Clin Exp Ophthalmol Date: 2019-10-24 Impact factor: 3.117