Literature DB >> 34256861

Synchronous and metachronous malignant melanomas arising in a human immunodeficiency virus-positive patient after the commencement of highly active antiretroviral therapy treatment: a case report.

Sharad P Paul1, Simon Briggs2, Michael Hitchcock2.   

Abstract

BACKGROUND: We present an unusual case of a patient who developed four melanomas within a few months of diagnosis with human immunodeficiency virus and commencement of highly active antiretroviral therapy therapy. The patient had no previous history of melanoma, and previous skin checks were normal. CASE
PRESENTATION: A 50-year-old Caucasian male drainlayer with Fitzpatrick type 2 skin presented for a routine skin examination. He had been diagnosed with human immunodeficiency virus 4 months earlier and commenced on highly active antiretroviral therapy therapy. He was found to have three melanomas (melanoma in situ stage) on excision biopsies, and when he presented for wider excisions of these sites a few weeks later, another new melanoma in situ was found. He had no other medical history of note, and no symptoms to report. He is being followed up 3-monthly.
CONCLUSIONS: This case of a human immunodeficiency virus-positive person presenting with four cutaneous melanomas-occurring in both synchronous and metachronous fashion within a 4-month period-is being presented both for its uniqueness and also to highlight the increased need for close skin surveillance in human immunodeficiency virus-positive patients.
© 2021. The Author(s).

Entities:  

Keywords:  Antiretroviral drugs; HIV; Melanoma; Skin cancer

Year:  2021        PMID: 34256861     DOI: 10.1186/s13256-021-02920-4

Source DB:  PubMed          Journal:  J Med Case Rep        ISSN: 1752-1947


  1 in total

Review 1.  Immunotherapy of advanced or metastatic melanoma.

Authors:  Jonathan Cebon; Craig Gedye; Thomas John; Ian D Davis
Journal:  Clin Adv Hematol Oncol       Date:  2007-12
  1 in total

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