Manisha Agarwal1, Mani Sachdeva1, Surendra Pal2, Harita Shah3, Madhu Kumar R4, Alay Banker3. 1. Vitreoretina Department, Dr Shroff's Charity Eye Hospital, New Delhi, India. 2. Vitreoretina department, Sankara Eye Hospital, Bengaluru, India. 3. Vitreoretinal department, Banker's Retina Clinic & Laser Centre, Ahmedabad, India. 4. Vitreoretina department, Sankara Eye Hospital, Guntur, India.
Abstract
PURPOSE: To report six patients with endogenous endophthalmitis as a complication of COVID-19 infection. METHODS: A multicentric retrospective database review of patients with a diagnosis of endogenous endophthalmitis and a history of COVID-19 infection. RESULTS: Four of six patients were diabetics. All presented after an average duration of 40 days (Range 17-90 days) of COVID-19 infection. Two of six patients had bilateral involvement. Five of six patients had received intravenous corticosteroid for COVID-19. Two of six vitreous samples showed fungi (Candida and Bipolaris species), two showed bacteria (Staphylococcus species) and two samples were culture negative. Control of infection with good visual outcome in four out of eight eyes. CONCLUSIONS: COVID-19 patients with a history of hospitalization and prolonged use of systemic corticosteroids and comorbidities, for example, diabetes mellitus have a high risk of endogenous endophthalmitis. A high index of clinical suspicion with timely intervention can salvage many eyes.
PURPOSE: To report six patients with endogenous endophthalmitis as a complication of COVID-19 infection. METHODS: A multicentric retrospective database review of patients with a diagnosis of endogenous endophthalmitis and a history of COVID-19 infection. RESULTS: Four of six patients were diabetics. All presented after an average duration of 40 days (Range 17-90 days) of COVID-19 infection. Two of six patients had bilateral involvement. Five of six patients had received intravenous corticosteroid for COVID-19. Two of six vitreous samples showed fungi (Candida and Bipolaris species), two showed bacteria (Staphylococcus species) and two samples were culture negative. Control of infection with good visual outcome in four out of eight eyes. CONCLUSIONS: COVID-19 patients with a history of hospitalization and prolonged use of systemic corticosteroids and comorbidities, for example, diabetes mellitus have a high risk of endogenous endophthalmitis. A high index of clinical suspicion with timely intervention can salvage many eyes.
Authors: Mohammad Javad Zibaeenezhad; Alireza Moaref; Firoozeh Abtahi; Mohsen Moghadami; Mohammad Karim Johari; Ali Ardekani; Mohammad Keshavarz Journal: Clin Case Rep Date: 2022-05-12