Jun Yeon Won1,2, Eui-Cheol Nam1,2, Taehun Lim3, Joon Bum Joo3, Seung-No Hong4, Woo Hyun Lee5,6. 1. Department of Otolaryngology, Kangwon National University Hospital, 156, Baengnyeong-ro, Chuncheon-Si, Gangwon-Do, 24289, Republic of Korea. 2. Department of Otolaryngology, Kangwon National University, Chuncheon, Korea. 3. Department of Otolaryngology, National Police Hospital, Seoul, Korea. 4. Department of Otorhinolaryngology, Seoul National University College of Medicine, Boramae Medical Center, Seoul, Korea. 5. Department of Otolaryngology, Kangwon National University Hospital, 156, Baengnyeong-ro, Chuncheon-Si, Gangwon-Do, 24289, Republic of Korea. sniper212@hanmail.net. 6. Department of Otolaryngology, Kangwon National University, Chuncheon, Korea. sniper212@hanmail.net.
Abstract
PURPOSE: The association between rhinosinusitis and obstructive sleep apnea (OSA) remains unclear. Here, we aimed to elucidate the association between sinus opacification and OSA severity. METHODS: Patients with snoring problems who visited our clinic from April 2018 to December 2020 were retrospectively enrolled. Among these patients, we included those who underwent a physical examination, overnight polysomnography, and osteomeatal-unit computed tomography. We evaluated the association between apnea-hypopnea index (AHI) and Lund-Mackay score (LMS). LMS ≥ 5 was considered indicative of sinus opacification. RESULTS: Among the 122 patients included in the study, LMS exhibited an increasing trend based on OSA severity. The LMS in the moderate OSA group was significantly higher than that in the no OSA group (P = 0.002), and the LMS in the severe OSA group was significantly higher than that in the no OSA (P < 0.001) and mild OSA (P = 0.006) groups. A correlation analysis revealed that AHI was significantly associated with body mass index (BMI) (r = 0.367, P < 0.001) and LMS (r = 0.255, P = 0.005). A multivariate analysis revealed that sinus opacification was associated with moderate and severe OSA [Adjusted odds ratio = 11.986 (P = 0.005) and 3.756 (P = 0.044), respectively] after adjusting for age, sex, BMI, smoking, hypertension, atopy, tonsil size, and palatal position. The effect of sinus opacification on OSA severity was comparable to that of overweight. CONCLUSION: Sinus opacification may increase OSA severity since moderate and severe OSA is independently associated with it.
PURPOSE: The association between rhinosinusitis and obstructive sleep apnea (OSA) remains unclear. Here, we aimed to elucidate the association between sinus opacification and OSA severity. METHODS: Patients with snoring problems who visited our clinic from April 2018 to December 2020 were retrospectively enrolled. Among these patients, we included those who underwent a physical examination, overnight polysomnography, and osteomeatal-unit computed tomography. We evaluated the association between apnea-hypopnea index (AHI) and Lund-Mackay score (LMS). LMS ≥ 5 was considered indicative of sinus opacification. RESULTS: Among the 122 patients included in the study, LMS exhibited an increasing trend based on OSA severity. The LMS in the moderate OSA group was significantly higher than that in the no OSA group (P = 0.002), and the LMS in the severe OSA group was significantly higher than that in the no OSA (P < 0.001) and mild OSA (P = 0.006) groups. A correlation analysis revealed that AHI was significantly associated with body mass index (BMI) (r = 0.367, P < 0.001) and LMS (r = 0.255, P = 0.005). A multivariate analysis revealed that sinus opacification was associated with moderate and severe OSA [Adjusted odds ratio = 11.986 (P = 0.005) and 3.756 (P = 0.044), respectively] after adjusting for age, sex, BMI, smoking, hypertension, atopy, tonsil size, and palatal position. The effect of sinus opacification on OSA severity was comparable to that of overweight. CONCLUSION: Sinus opacification may increase OSA severity since moderate and severe OSA is independently associated with it.
Authors: Chelle P Wilhelm; Richard D deShazo; Sadeka Tamanna; M Iftekhar Ullah; Leigh Baldwin Skipworth Journal: Ann Allergy Asthma Immunol Date: 2015-08 Impact factor: 6.347
Authors: Kannan Ramar; Leslie C Dort; Sheri G Katz; Christopher J Lettieri; Christopher G Harrod; Sherene M Thomas; Ronald D Chervin Journal: J Clin Sleep Med Date: 2015-07-15 Impact factor: 4.062