BongKyoo Choi1,2, Ji Hyeun Shin3, Jee Eun Lee4, Sang Baek Koh5. 1. Department of Research and Development, GC Pharma, Yongin, Korea. 2. Department of Medicine, University of California, Irvine, CA, USA. b.choi@gccorp.com. 3. Department of Pharmacovigilance, LSK Global PS, Seoul, Korea. 4. Department of Clinical and Regulatory Affairs, LG Chem Ltd, Seoul, Korea. 5. Department of Preventive Medicine, Wonju College of Medicine, Yonsei University, Wonju, Korea.