Literature DB >> 3425381

Severe liver damage caused by therapeutic doses of acetaminophen.

C H Florén1, P Thesleff, A Nilsson.   

Abstract

Two patients who ingested therapeutic doses of acetaminophen and who developed a severe hepatotoxicity are reported. Both patients had a rather high alcohol consumption, which probably made them susceptible to the toxic effects of acetaminophen.

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Year:  1987        PMID: 3425381     DOI: 10.1111/j.0954-6820.1987.tb10672.x

Source DB:  PubMed          Journal:  Acta Med Scand        ISSN: 0001-6101


  4 in total

1.  Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi.

Authors:  C J Henderson; C R Wolf; N Kitteringham; H Powell; D Otto; B K Park
Journal:  Proc Natl Acad Sci U S A       Date:  2000-11-07       Impact factor: 11.205

2.  Patterns of acetaminophen use exceeding 4 grams daily in a hospitalized population at a tertiary care center.

Authors:  Jesse M Civan; Victor Navarro; Steven K Herrine; Jeffrey M Riggio; Paul Adams; Simona Rossi
Journal:  Gastroenterol Hepatol (N Y)       Date:  2014-01

Review 3.  Paracetamol, alcohol and the liver.

Authors:  L F Prescott
Journal:  Br J Clin Pharmacol       Date:  2000-04       Impact factor: 4.335

Review 4.  Are some people at increased risk of paracetamol-induced liver injury? A critical review of the literature.

Authors:  Thomas M Caparrotta; Daniel J Antoine; James W Dear
Journal:  Eur J Clin Pharmacol       Date:  2017-10-24       Impact factor: 2.953

  4 in total

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