| Literature DB >> 34251046 |
Emma F Magavern1, Deepti Gurdasani1, Fu L Ng2, Sandra Soo-Jin Lee3.
Abstract
Pharmacogenomics is increasingly moving into mainstream clinical practice. Careful consideration must be paid to inclusion of diverse populations in research, translation and implementation, in the historical and social context of population stratification, to ensure that this leads to improvements in healthcare for all rather than increased health disparities. This review takes a broad and critical approach to the current role of diversity in pharmacogenomics and addresses potential pitfalls in order to raise awareness for prescribers. It also emphasizes evidence gaps and suggests approaches that may minimize negative consequences and promote health equality.Entities:
Keywords: bioethics; pharmacogenomics; pharmacotherapy; therapeutics
Mesh:
Year: 2021 PMID: 34251046 PMCID: PMC8752640 DOI: 10.1111/bcp.14983
Source DB: PubMed Journal: Br J Clin Pharmacol ISSN: 0306-5251 Impact factor: 4.335