Literature DB >> 34244744

A multicentre point prevalence survey (PPS) of antimicrobial use amongst admitted patients in tertiary care centres in India.

Aditi M Panditrao1, Nusrat Shafiq1, Suparna Chatterjee2, Ashish Pathak3, Niyati Trivedi4, Balakrishnan Sadasivam5, Nilima Kshirsagar6, Rajni Kaul6, Manisha Biswal1, Ashish Kakkar1, Samir Malhotra1, Pankaj Arora1, Shweta Talati1, Navneet Dhaliwal1, Avijit Hazra2, Ratinder Jhaj5, Ahmad Najmi4, Navin Pandey1, Raja Chakraverty2, Saman Pathan5, Janki Chauhan4, Aditya Mathur3.   

Abstract

OBJECTIVES: Data from point prevalence surveys (PPSs) in India are scarce. Conducting PPSs is especially challenging in the absence of electronic medical records, a lack of dedicated resources and a high patient load in resource-poor settings. This multicentre survey was conducted to provide background data for planning and strengthening antimicrobial stewardship programmes across the country.
METHODS: This inpatient PPS was conducted over 2 weeks in May 2019 simultaneously across five study centres in India. Data about patient characteristics, indications for antimicrobials use and details of each antimicrobial prescribed including supportive investigation reports were collected in predesigned forms.
RESULTS: A total of 3473 admitted patients in wards and ICUs were covered across five study centres. Of these, 1747 (50.3%) patients were on antimicrobials, with 46.9% patients being on two or more antimicrobials. Out of the total antimicrobials prescribed, 40.2% of the antimicrobials were prescribed for community-acquired infection requiring hospitalization followed by surgical prophylaxis (32.6%). Third-generation cephalosporins and drugs from the 'Watch' category were prescribed most commonly. Only 22.8% of the antimicrobials were based on microbiology reports.
CONCLUSIONS: The survey demonstrated a high use of antimicrobials in admitted patients with a considerable proportion of drugs from the 'Watch' category. The targets for interventions that emerged from the survey were: improving surgical prophylaxis, decreasing double anaerobic cover, initiating culture of sending cultures and de-escalation with targeted therapy.
© The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Entities:  

Year:  2021        PMID: 34244744     DOI: 10.1093/jac/dkaa533

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  1 in total

1.  Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh.

Authors:  Md Mahbubur Rashid; Zubair Akhtar; Sukanta Chowdhury; Md Ariful Islam; Shahana Parveen; Probir Kumar Ghosh; Aninda Rahman; Zobaidul Haque Khan; Khaleda Islam; Nitish Debnath; Mahmudur Rahman; Fahmida Chowdhury
Journal:  Antibiotics (Basel)       Date:  2022-06-16
  1 in total

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