Literature DB >> 34244480

Thoracic ligamentum flavum ossification: a rare cause of spinal cord injury without tomographic evidence of trauma in a Caucasian patient. Case report and literature review.

Guillermo Alejandro Ricciardi1,2, Ignacio Gabriel Garfinkel3,4, Gabriel Genaro Carrioli3,4, Daniel Oscar Ricciardi3,4.   

Abstract

INTRODUCTION: Acute spinal cord injury without tomographic evidence of vertebral fracture or dislocation in patients post trauma can represent a diagnostic challenge for the treating physician. The ossification of thoracic ligamentum flavum has been widely published as a cause of thoracic myelopathy, however its association with acute traumatic spinal cord injury is limited to isolated cases. CASE
PRESENTATION: we report a Caucasian 37-year-old man who suffered a high-energy thoracolumbar spine trauma in a motorcycle accident with acute paraplegia. He presented ossification of the ligamentum flavum between the thoracic vertebrae T10 and T11 with a decrease in the diameter of the vertebral canal as the only pathological finding. We treated the patient with early surgical release before 72 h of trauma. We performed a posterior approach with hemilaminectomy and T10-T11 flavectomy. Arthrodesis was done with T10-T11 pedicle screws. Postoperative neurological status improved from ASIA Impairment Scale (AIS) A to C with severe functional dependence. DISCUSSION: Ossification of the ligamentum flavum should be considered in the differential diagnosis in patients presenting with acute traumatic spinal cord injury without tomographic evidence of trauma. A proper diagnosis in time is the key to decision making and treatment of spinal cord injury. Especially in adult patients, we must consider nontraumatic associated factors that could be involved in the spinal cord injury mechanism, such as ossification of the ligamentum flavum.
© 2021. The Author(s), under exclusive licence to International Spinal Cord Society.

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Mesh:

Year:  2021        PMID: 34244480      PMCID: PMC8271015          DOI: 10.1038/s41394-021-00422-5

Source DB:  PubMed          Journal:  Spinal Cord Ser Cases        ISSN: 2058-6124


  44 in total

1.  Clinical Guideline for Treatment of Symptomatic Thoracic Spinal Stenosis.

Authors:  Zhong-qiang Chen; Chui-guo Sun
Journal:  Orthop Surg       Date:  2015-08       Impact factor: 2.071

Review 2.  Untreated hypophosphatemic vitamin D-resistant rickets with symptomatic ossification of the ligamentum flavum.

Authors:  H Matsui; Y Katoh; H Tsuji
Journal:  J Spinal Disord       Date:  1991-03

3.  Ossification of the ligamentum flavum in a Caucasian man.

Authors:  Risheng Xu; Daniel M Sciubba; Ziya L Gokaslan; Ali Bydon
Journal:  J Neurosurg Spine       Date:  2008-11

4.  Clinically significant radiographic parameter for thoracic myelopathy caused by ossification of the ligamentum flavum.

Authors:  Byung-Jou Lee; Jin Hoon Park; Sang-Ryong Jeon; Seung-Chul Rhim; Sung Woo Roh
Journal:  Eur Spine J       Date:  2018-09-06       Impact factor: 3.134

Review 5.  A systematic review of complications in thoracic spine surgery for ossification of ligamentum flavum.

Authors:  Xiaofei Hou; Zhongqiang Chen; Chuiguo Sun; Guangwu Zhang; Sijun Wu; Zheng Liu
Journal:  Spinal Cord       Date:  2017-12-28       Impact factor: 2.772

6.  Spinal cord injury without radiographic abnormality in adults.

Authors:  S K Gupta; K Rajeev; V K Khosla; B S Sharma; S N Mathuriya; A Pathak; M K Tewari; A Kumar
Journal:  Spinal Cord       Date:  1999-10       Impact factor: 2.772

7.  [Instrument for the functional evaluation of disability rehabilitation. Study on the reliability and clinical experience with the use of functional independence measure].

Authors:  C Paolinelli; P González; M E Doniez; T Donoso; V Salinas
Journal:  Rev Med Chil       Date:  2001-01       Impact factor: 0.553

8.  Rotational stress: role in development of ossification of posterior longitudinal ligament and ligamentum flavum.

Authors:  Jian Chen; Xinwei Wang; Ce Wang; Wen Yuan
Journal:  Med Hypotheses       Date:  2010-09-06       Impact factor: 1.538

9.  The adult spinal cord injury without radiographic abnormalities syndrome: magnetic resonance imaging and clinical findings in adults with spinal cord injuries having normal radiographs and computed tomography studies.

Authors:  Georgios B Kasimatis; Elias Panagiotopoulos; Panagiotis Megas; Charalambos Matzaroglou; John Gliatis; Minos Tyllianakis; Elias Lambiris
Journal:  J Trauma       Date:  2008-07

10.  Prevalence, distribution, and morphology of ossification of the ligamentum flavum: a population study of one thousand seven hundred thirty-six magnetic resonance imaging scans.

Authors:  Jiong Jiong Guo; Keith D K Luk; Jaro Karppinen; Huilin Yang; Kenneth M C Cheung
Journal:  Spine (Phila Pa 1976)       Date:  2010-01-01       Impact factor: 3.468

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