Literature DB >> 34241735

Arresting metastasis within the microcirculation.

Angelos Varotsos Vrynas1, Julia Perea Paizal1,2, Chris Bakal2, Sam H Au3.   

Abstract

The behaviour of circulating tumour cells in the microcirculation remains poorly understood. Growing evidence suggests that biomechanical adaptations and interactions with blood components, i.e. immune cells and platelets within capillary beds, may add more complexity to CTCs journey towards metastasis. Revisiting how these mediators impact the ability of circulating tumour cells to survive and metastasise, will be vital to understand the role of microcirculation and advance our knowledge on metastasis.
© 2021. The Author(s).

Entities:  

Keywords:  Biomechanics; Cancer; Circulating tumour cells; Immune cells; Metastasis; Microvasculature; Platelets

Year:  2021        PMID： 34241735     DOI： 10.1007/s10585-021-10109-8

Source DB:  PubMed          Journal:  Clin Exp Metastasis        ISSN： 0262-0898            Impact factor:   5.150


  19 in total

1.  YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation.

Authors:  David C Benjamin; Joon Ho Kang; Bashar Hamza; Emily M King; John M Lamar; Scott R Manalis; Richard O Hynes
Journal:  Cancer Res       Date:  2020-06-26       Impact factor: 12.701

2.  RhoA-stimulated intra-capillary morphology switch facilitates the arrest of individual circulating tumor cells.

Authors:  Xi Huang; Yu Yang; Yuwei Zhao; Dan Cao; Xiaolin Ai; Anqi Zeng; Maling Gou; Lulu Cai; Hanshuo Yang; Chengjian Zhao
Journal:  Int J Cancer       Date:  2018-01-19       Impact factor: 7.396

3.  Visualization of immediate immune responses to pioneer metastatic cells in the lung.

Authors:  Mark B Headley; Adriaan Bins; Alyssa Nip; Edward W Roberts; Mark R Looney; Audrey Gerard; Matthew F Krummel
Journal:  Nature       Date:  2016-03-16       Impact factor: 49.962

4.  Metastasis: quantitative analysis of distribution and fate of tumor emboli labeled with 125 I-5-iodo-2'-deoxyuridine.

Authors:  I J Fidler
Journal:  J Natl Cancer Inst       Date:  1970-10       Impact factor: 13.506

5.  Quantitation of cell shedding into efferent blood of mammary adenocarcinoma.

Authors:  T P Butler; P M Gullino
Journal:  Cancer Res       Date:  1975-03       Impact factor: 12.701

6.  Real-time imaging reveals the single steps of brain metastasis formation.

Authors:  Yvonne Kienast; Louisa von Baumgarten; Martin Fuhrmann; Wolfgang E F Klinkert; Roland Goldbrunner; Jochen Herms; Frank Winkler
Journal:  Nat Med       Date:  2009-12-20       Impact factor: 53.440

7.  Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases.

Authors:  K J Luzzi; I C MacDonald; E E Schmidt; N Kerkvliet; V L Morris; A F Chambers; A C Groom
Journal:  Am J Pathol       Date:  1998-09       Impact factor: 4.307

8.  Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation.

Authors:  Devon L Moose; Benjamin L Krog; Tae-Hyung Kim; Lei Zhao; Sophia Williams-Perez; Gretchen Burke; Lillian Rhodes; Marion Vanneste; Patrick Breheny; Mohammed Milhem; Christopher S Stipp; Amy C Rowat; Michael D Henry
Journal:  Cell Rep       Date:  2020-03-17       Impact factor: 9.423

9.  Circulating Tumor Cells from Different Vascular Sites Exhibit Spatial Heterogeneity in Epithelial and Mesenchymal Composition and Distinct Clinical Significance in Hepatocellular Carcinoma.

Authors:  Yun-Fan Sun; Wei Guo; Yang Xu; Yin-Hong Shi; Zi-Jun Gong; Yuan Ji; Min Du; Xin Zhang; Bo Hu; Ao Huang; George G Chen; Paul B S Lai; Ya Cao; Shuang-Jian Qiu; Jian Zhou; Xin-Rong Yang; Jia Fan
Journal:  Clin Cancer Res       Date:  2017-10-25       Impact factor: 12.531

10.  Direct evidence that tumor cells soften when navigating confined spaces.

Authors:  Carmela Rianna; Manfred Radmacher; Sanjay Kumar
Journal:  Mol Biol Cell       Date:  2020-01-29       Impact factor: 4.138
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