Literature DB >> 34240239

[The Iceman : Life scenarios and pathological findings from 30 years of research on the glacier mummy "Ötzi"].

Andreas G Nerlich1, Eduard Egarter Vigl2, Angelika Fleckinger3, Martina Tauber4, Oliver Peschel5.   

Abstract

The comprehensive investigation of the excellently preserved mummy of Ötzi, the Iceman, and his equipment over the last 30 years has provided a wealth of information about the life and disease of this late Neolithic individual. This research has indicated that his origin was from a local southern Alpine population, that he grew up in the valleys of the Southern Alps, and that he had considerable local mobility. He had well-balanced nutrition with a mixed vegetable and animal diet. He was very mobile in the alpine terrain and of athletic constitution. The Iceman suffered from mild to moderate degenerative joint disease primarily of the right hip joint, slight spondylosis of the cervical and lumbar spine, a minor focal (premature) arteriosclerosis, lung anthracosis and possibly silicosis, previous pleuritic inflammation (possibly of post-specific origin), intestinal infections of the stomach by Helicobacter pylori and Trichuris trichiura worm infestation in the intestines, a mild osteomalacia of cancellous bone, and diverse pathologies of his teeth with dental caries and periodontitis, as well as hair anomalies. The presence of borreliosis is still under debate. As potential remedies, the Iceman carried some anthelmintic substances with him: a birch polypore and an anthelmintic fern. The numerous tattoos may also have had therapeutic effects. Finally, the last days of Ötzi could be reconstructed quite precisely: his gastrointestinal content indicates that the Iceman moved from Alpine heights to a lower location and then again up to the glacier region where he died. During this journey he encountered two attacks: the first, several days before his death, lead to a stabbing wound in his right hand; the second was an arrow hit that wounded the Iceman lethally at his left axilla by laceration of the subclavian artery.

Entities:  

Keywords:  Historic remedies; Infectious diseases; Mummy research; Paleopathology; Trauma sequels

Year:  2021        PMID: 34240239     DOI: 10.1007/s00292-021-00961-6

Source DB:  PubMed          Journal:  Pathologe        ISSN: 0172-8113            Impact factor:   1.011


  23 in total

1.  The omnivorous Tyrolean Iceman: colon contents (meat, cereals, pollen, moss and whipworm) and stable isotope analyses.

Authors:  J H Dickson; K Oeggl; T G Holden; L L Handley; T C O'Connell; T Preston
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2000-12-29       Impact factor: 6.237

2.  Paleoproteomic study of the Iceman's brain tissue.

Authors:  Frank Maixner; Thorsten Overath; Dennis Linke; Marek Janko; Gea Guerriero; Bart H J van den Berg; Bjoern Stade; Petra Leidinger; Christina Backes; Marta Jaremek; Benny Kneissl; Benjamin Meder; Andre Franke; Eduard Egarter-Vigl; Eckart Meese; Andreas Schwarz; Andreas Tholey; Albert Zink; Andreas Keller
Journal:  Cell Mol Life Sci       Date:  2013-06-06       Impact factor: 9.261

3.  Fatty acid composition and preservation of the Tyrolean Iceman and other mummies.

Authors:  Athanasios Makristathis; Josef Schwarzmeier; Robert M Mader; Kurt Varmuza; Ingrid Simonitsch; Jose Chavez Chavez; Werner Platzer; Hans Unterdorfer; Richard Scheithauer; Anatoly Derevianko; Horst Seidler
Journal:  J Lipid Res       Date:  2002-12       Impact factor: 5.922

4.  Histological investigations on the Tyrolean Ice Man.

Authors:  M W Hess; G Klima; K Pfaller; K H Künzel; O Gaber
Journal:  Am J Phys Anthropol       Date:  1998-08       Impact factor: 2.868

5.  Nanostructure and mechanics of mummified type I collagen from the 5300-year-old Tyrolean Iceman.

Authors:  Marek Janko; Albert Zink; Alexander M Gigler; Wolfgang M Heckl; Robert W Stark
Journal:  Proc Biol Sci       Date:  2010-03-31       Impact factor: 5.349

6.  The 5300-year-old Helicobacter pylori genome of the Iceman.

Authors:  Frank Maixner; Ben Krause-Kyora; Dmitrij Turaev; Alexander Herbig; Michael R Hoopmann; Janice L Hallows; Ulrike Kusebauch; Eduard Egarter Vigl; Peter Malfertheiner; Francis Megraud; Niall O'Sullivan; Giovanna Cipollini; Valentina Coia; Marco Samadelli; Lars Engstrand; Bodo Linz; Robert L Moritz; Rudolf Grimm; Johannes Krause; Almut Nebel; Yoshan Moodley; Thomas Rattei; Albert Zink
Journal:  Science       Date:  2016-01-08       Impact factor: 47.728

7.  Man from the Hauslabjoch.

Authors:  O Gaber; K H Künzel
Journal:  Exp Gerontol       Date:  1998 Nov-Dec       Impact factor: 4.032

8.  Scalable metagenomic taxonomy classification using a reference genome database.

Authors:  Sasha K Ames; David A Hysom; Shea N Gardner; G Scott Lloyd; Maya B Gokhale; Jonathan E Allen
Journal:  Bioinformatics       Date:  2013-07-04       Impact factor: 6.937

9.  New glacier evidence for ice-free summits during the life of the Tyrolean Iceman.

Authors:  Pascal Bohleber; Margit Schwikowski; Martin Stocker-Waldhuber; Ling Fang; Andrea Fischer
Journal:  Sci Rep       Date:  2020-12-17       Impact factor: 4.379

10.  The musculoskeletal abnormalities of the Similaun Iceman ("ÖTZI"): clues to chronic pain and possible treatments.

Authors:  Walter F Kean; Shannon Tocchio; Mary Kean; K D Rainsford
Journal:  Inflammopharmacology       Date:  2012-10-25       Impact factor: 4.473

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