Literature DB >> 34240215

MGMT testing always worth an emotion.

Monika E Hegi1, Koichi Ichimura2.   

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Year:  2021        PMID： 34240215      PMCID： PMC8408863          DOI： 10.1093/neuonc/noab163

Source DB:  PubMed          Journal:  Neuro Oncol        ISSN： 1522-8517            Impact factor:   13.029


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  10 in total

1.  MGMT Promoter Methylation Cutoff with Safety Margin for Selecting Glioblastoma Patients into Trials Omitting Temozolomide: A Pooled Analysis of Four Clinical Trials.

Authors:  Monika E Hegi; Els Genbrugge; Thierry Gorlia; Roger Stupp; Mark R Gilbert; Olivier L Chinot; L Burt Nabors; Greg Jones; Wim Van Criekinge; Josef Straub; Michael Weller
Journal:  Clin Cancer Res       Date:  2018-12-04       Impact factor: 12.531

2.  A distinct region of the MGMT CpG island critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts.

Authors:  Deborah S Malley; Rifat A Hamoudi; Sylvia Kocialkowski; Danita M Pearson; Vincent Peter Collins; Koichi Ichimura
Journal:  Acta Neuropathol       Date:  2011-02-03       Impact factor: 17.088

3.  Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial.

Authors:  Annika Malmström; Bjørn Henning Grønberg; Christine Marosi; Roger Stupp; Didier Frappaz; Henrik Schultz; Ufuk Abacioglu; Björn Tavelin; Benoit Lhermitte; Monika E Hegi; Johan Rosell; Roger Henriksson
Journal:  Lancet Oncol       Date:  2012-08-08       Impact factor: 41.316

4.  Platform trials arrive on time for glioblastoma.

Authors:  Brian M Alexander; Timothy F Cloughesy
Journal:  Neuro Oncol       Date:  2018-05-18       Impact factor: 12.300

5.  MGMT gene silencing and benefit from temozolomide in glioblastoma.

Authors:  Monika E Hegi; Annie-Claire Diserens; Thierry Gorlia; Marie-France Hamou; Nicolas de Tribolet; Michael Weller; Johan M Kros; Johannes A Hainfellner; Warren Mason; Luigi Mariani; Jacoline E C Bromberg; Peter Hau; René O Mirimanoff; J Gregory Cairncross; Robert C Janzer; Roger Stupp
Journal:  N Engl J Med       Date:  2005-03-10       Impact factor: 91.245

6.  MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 or IDH2 mutations.

Authors:  Shani Mulholland; Danita M Pearson; Rifat A Hamoudi; Deborah S Malley; Caroline M Smith; Jamie M J Weaver; David T W Jones; Sylvia Kocialkowski; L Magnus Bäcklund; V Peter Collins; Koichi Ichimura
Journal:  Int J Cancer       Date:  2012-01-11       Impact factor: 7.316

7.  Prognostic value of test(s) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide.

Authors:  Alexandra McAleenan; Claire Kelly; Francesca Spiga; Ashleigh Kernohan; Hung-Yuan Cheng; Sarah Dawson; Lena Schmidt; Tomos Robinson; Sebastian Brandner; Claire L Faulkner; Christopher Wragg; Sarah Jefferies; Amy Howell; Luke Vale; Julian P T Higgins; Kathreena M Kurian
Journal:  Cochrane Database Syst Rev       Date:  2021-03-12

8.  Prognostic and predictive markers in recurrent high grade glioma; results from the BR12 randomised trial.

Authors:  Vincent Peter Collins; Koichi Ichimura; Ying Di; Danita Pearson; Ray Chan; Lindsay C Thompson; Rhian Gabe; Michael Brada; Sally P Stenning
Journal:  Acta Neuropathol Commun       Date:  2014-06-20       Impact factor: 7.801

Review 9.  DNA Methylation Cancer Biomarkers: Translation to the Clinic.

Authors:  Warwick J Locke; Dominic Guanzon; Chenkai Ma; Yi Jin Liew; Konsta R Duesing; Kim Y C Fung; Jason P Ross
Journal:  Front Genet       Date:  2019-11-14       Impact factor: 4.599

10.  MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Systematic Review.

Authors:  Sebastian Brandner; Alexandra McAleenan; Claire Kelly; Francesca Spiga; Hung-Yuan Cheng; Sarah Dawson; Lena Schmidt; Claire L Faulkner; Christopher Wragg; Sarah Jefferies; Julian P T Higgins; Kathreena M Kurian
Journal:  Neuro Oncol       Date:  2021-09-01       Impact factor: 12.300
  10 in total
  1 in total

1.  Association between eight hypermethylation-related genes and gastric cancer: a systematic review and meta-analysis.

Authors:  Chenhui Ma; Bofang Wang; Weigao Pu; Huanhuan Ma; Kewei Song; Na Wang; Xiaobo Deng; Hao Chen
Journal:  Transl Cancer Res       Date:  2022-07       Impact factor: 0.496
  1 in total

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