Mohammadreza Chavoshi1, Seyed Ali Mirshahvalad2, Mehrzad Mahdizadeh3, Fatemeh Zamani3. 1. Department of Radiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2. Department of Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. 3. Department of Radiology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Abstract
Background: The present study aimed to perform a meta-analysis on the performance of Graf's ultrasonography method in the detection of developmental dysplasia of the hip (DDH). Methods: A query was conducted on electronic bibliographic databases until the end of October 2020. The inclusion criteria entailed: 1. the use of Graf method in less than 12 weeks of age, 2. the use of follow-up as reference test, and 3. provision of crude data. Pooled diagnostic performance measures were calculated. Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) checklist was utilized to assess the quality of the included studies. The hierarchical summary receiver-operating characteristic (HROC) curves were also drawn. Results: Six articles (including seven populations, 11,012 patients) were considered eligible. The pooled sensitivity and specificity were obtained at 93% (95% CI: 0.57-0.99) and 97% (95% CI:0.86-0.99), respectively (area under curve= 0.99). The pooled positive and negative likelihood ratio, as well as diagnostic odds ratio, was reported as 28.4, 0.07, and 396, respectively. Conclusion: As evidenced by the obtained results, Graf's method is a useful ultrasonography technique with acceptable accuracy for screening DDH in neonates. However, there are uncertainties about the best population and age for screening. Furthermore, more attention should be paid to the proper training of this method to reduce the number of operator errors.
Background: The present study aimed to perform a meta-analysis on the performance of Graf's ultrasonography method in the detection of developmental dysplasia of the hip (DDH). Methods: A query was conducted on electronic bibliographic databases until the end of October 2020. The inclusion criteria entailed: 1. the use of Graf method in less than 12 weeks of age, 2. the use of follow-up as reference test, and 3. provision of crude data. Pooled diagnostic performance measures were calculated. Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) checklist was utilized to assess the quality of the included studies. The hierarchical summary receiver-operating characteristic (HROC) curves were also drawn. Results: Six articles (including seven populations, 11,012 patients) were considered eligible. The pooled sensitivity and specificity were obtained at 93% (95% CI: 0.57-0.99) and 97% (95% CI:0.86-0.99), respectively (area under curve= 0.99). The pooled positive and negative likelihood ratio, as well as diagnostic odds ratio, was reported as 28.4, 0.07, and 396, respectively. Conclusion: As evidenced by the obtained results, Graf's method is a useful ultrasonography technique with acceptable accuracy for screening DDH in neonates. However, there are uncertainties about the best population and age for screening. Furthermore, more attention should be paid to the proper training of this method to reduce the number of operator errors.
Authors: David Moher; Larissa Shamseer; Mike Clarke; Davina Ghersi; Alessandro Liberati; Mark Petticrew; Paul Shekelle; Lesley A Stewart Journal: Syst Rev Date: 2015-01-01
Authors: Trevor A McGrath; Mostafa Alabousi; Becky Skidmore; Daniël A Korevaar; Patrick M M Bossuyt; David Moher; Brett Thombs; Matthew D F McInnes Journal: Syst Rev Date: 2017-10-10