William V McCall1, Ben Porter2, Ashley R Pate3, Courtney J Bolstad3, Christopher W Drapeau4,5, Andrew D Krystal6, Ruth M Benca7, Meredith E Rumble8, Michael R Nadorff3,9. 1. Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, Georgia, USA. 2. Social Science Research Center, Mississippi State University, Mississippi State, Mississippi, USA. 3. Department of Psychology, Mississippi State University, Mississippi State, Mississippi, USA. 4. Department of Health Policy and Management, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, Indiana, USA. 5. Division of Mental Health and Addiction, Indiana Family and Social Services Administration, Indianapolis, Indiana, USA. 6. University of California San Francisco, San Francisco, California, USA. 7. Department of Psychiatry and Human Behavior, University of California, Irvine, California, USA. 8. Department of Psychiatry, University of Wisconsin, Madison, Wisconsin, USA. 9. Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.
Abstract
INTRODUCTION: Progress reducing suicide death will require randomized clinical trials (RCTs) specifically targeting suicide risk. Even large RCTs may not stipulate suicide death as the primary outcome, as suicide death is relatively uncommon. Therefore, RCTs may need to specify suicidal ideation as a proxy indicator of risk. There is no consensus on the best tool for measuring suicidal ideation within RCTs. We contrasted the psychometric performance of three suicidal ideation measures to address this need. METHODS: We applied item response theory to the Beck Scale for Suicide Ideation (BSSI), the Columbia-Suicide Severity Rating Scale (C-SSRS), and the suicide item of the Hamilton Rating Scale for Depression (HRSD) for 101 outpatients with depression and suicidal ideation participating in a RCT with suicidal ideation as the primary outcome. RESULTS: All measures of suicidal ideation were equally able to detect low and very high levels of suicidal ideation. CONCLUSIONS: The choice of the specific measure of suicidal ideation in a clinical trial may be dictated by time and financial resources versus the need for granularity in the interpretation of the scores.
INTRODUCTION: Progress reducing suicide death will require randomized clinical trials (RCTs) specifically targeting suicide risk. Even large RCTs may not stipulate suicide death as the primary outcome, as suicide death is relatively uncommon. Therefore, RCTs may need to specify suicidal ideation as a proxy indicator of risk. There is no consensus on the best tool for measuring suicidal ideation within RCTs. We contrasted the psychometric performance of three suicidal ideation measures to address this need. METHODS: We applied item response theory to the Beck Scale for Suicide Ideation (BSSI), the Columbia-Suicide Severity Rating Scale (C-SSRS), and the suicide item of the Hamilton Rating Scale for Depression (HRSD) for 101 outpatients with depression and suicidal ideation participating in a RCT with suicidal ideation as the primary outcome. RESULTS: All measures of suicidal ideation were equally able to detect low and very high levels of suicidal ideation. CONCLUSIONS: The choice of the specific measure of suicidal ideation in a clinical trial may be dictated by time and financial resources versus the need for granularity in the interpretation of the scores.
Authors: Daun Shin; Kyungdo Kim; Seung-Bo Lee; Changwoo Lee; Ye Seul Bae; Won Ik Cho; Min Ji Kim; C Hyung Keun Park; Eui Kyu Chie; Nam Soo Kim; Yong Min Ahn Journal: Front Psychiatry Date: 2022-05-24 Impact factor: 5.435