Literature DB >> 34233522

Effects of bone morphogenetic proteins on epithelial repair.

Yu Hou1,2, Yu-Xi He1, Jia-Hao Zhang1,2, Shu-Rong Wang1, Yan Zhang1.   

Abstract

Epithelial tissue has important functions such as protection, secretion, and sensation. Epithelial damage is involved in various pathological processes. Bone morphogenetic proteins (BMPs) are a class of growth factors with multiple functions. They play important roles in epithelial cells, including in differentiation, proliferation, and migration during the repair of the epithelium. This article reviews the functions and mechanisms of the most profoundly studied BMPs in the process of epithelial damage repair and their clinical significance.

Entities:  

Keywords:  Bone morphogenetic protein; epithelium; wound healing

Mesh:

Substances:

Year:  2021        PMID: 34233522      PMCID: PMC8581822          DOI: 10.1177/15353702211028193

Source DB:  PubMed          Journal:  Exp Biol Med (Maywood)        ISSN: 1535-3699


  67 in total

1.  Blocking TGF-β and BMP SMAD-dependent cell differentiation is a master key to expand all kinds of epithelial stem cells.

Authors:  Boris Guyot; Véronique Maguer-Satta
Journal:  Stem Cell Investig       Date:  2016-12-08

2.  Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin.

Authors:  Dallas P Veitch; Pasi Nokelainen; Kelly A McGowan; Thuong-Thuong Nguyen; Ngon E Nguyen; Robert Stephenson; William N Pappano; Douglas R Keene; Suzanne M Spong; Daniel S Greenspan; Paul R Findell; M Peter Marinkovich
Journal:  J Biol Chem       Date:  2002-12-07       Impact factor: 5.157

3.  Impact of selective anti-BMP9 treatment on tumor cells and tumor angiogenesis.

Authors: 
Journal:  Mol Oncol       Date:  2016-12       Impact factor: 6.603

4.  Bone Morphogenetic Protein-7 Inhibits EMT-Associated Genes in Breast Cancer.

Authors:  Xuexiang Ying; Yunpo Sun; Pingqing He
Journal:  Cell Physiol Biochem       Date:  2015-10-05

5.  The involvement of growth differentiation factor 5 (GDF5) and aggrecan in the epithelial-mesenchymal transition of salivary gland pleomorphic adenoma.

Authors:  Anca Stefania Enescu; C L Mărgăritescu; Monica Mihaela Crăiţoiu; Aurelia Enescu; Ştefania Crăiţoiu
Journal:  Rom J Morphol Embryol       Date:  2013       Impact factor: 1.033

6.  BMP-2 suppresses renal interstitial fibrosis by regulating epithelial-mesenchymal transition.

Authors:  Yu-Lin Yang; Hong-Zen Ju; Shu-Fen Liu; Tao-Chen Lee; Yuan-Wei Shih; Lea-Yea Chuang; Jinn-Yuh Guh; Ya-Ying Yang; Tung-Nan Liao; Tsung-Jen Hung; Min-Yuan Hung
Journal:  J Cell Biochem       Date:  2011-09       Impact factor: 4.429

7.  A Rare Colon Cancer with Ossification: Pathogenetic Analysis of Bone Formation.

Authors:  Byeong-Joo Noh; Youn Wha Kim; Yong-Koo Park
Journal:  Ann Clin Lab Sci       Date:  2016-07       Impact factor: 1.256

8.  A distinct regulatory region of the Bmp5 locus activates gene expression following adult bone fracture or soft tissue injury.

Authors:  Catherine A Guenther; Zhen Wang; Emma Li; Misha C Tran; Catriona Y Logan; Roel Nusse; Luiz Pantalena-Filho; George P Yang; David M Kingsley
Journal:  Bone       Date:  2015-04-14       Impact factor: 4.398

9.  ING5 inhibits cancer aggressiveness via preventing EMT and is a potential prognostic biomarker for lung cancer.

Authors:  Feng Zhang; Xutao Zhang; Jin Meng; Yong Zhao; Xinli Liu; Yanxia Liu; Yukun Wang; Yuhua Li; Yang Sun; Zhipeng Wang; Qibing Mei; Tao Zhang
Journal:  Oncotarget       Date:  2015-06-30

10.  Upregulation of bone morphogenetic protein 1 is associated with poor prognosis of late-stage gastric Cancer patients.

Authors:  Yung-Yu Hsieh; Shui-Yi Tung; Hung-Yu Pan; Chih-Wei Yen; Huang-Wei Xu; Yi-Fang Deng; Ying-Jhen Lin; Wan-Ting Hsu; Cheng-Shyong Wu; Chin Li
Journal:  BMC Cancer       Date:  2018-05-02       Impact factor: 4.430

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