Literature DB >> 34233170

The therapeutic promises of NAD+ boosters.

Claudia Montllor-Albalate1, Zehan Song1, Danica Chen2.   

Abstract

Numerous preclinical studies implicate the decline in NAD+ signaling in developing aging- and obesity-associated metabolic disorders. Yoshino et al. (2021) now provide the clinical evidence that an NAD+ booster increases muscle insulin sensitivity in postmenopausal prediabetic women, validating the therapeutic promises of NAD+ boosters in humans.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2021        PMID: 34233170     DOI: 10.1016/j.cmet.2021.06.008

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  1 in total

1.  Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis.

Authors:  Christopher A Koczor; Kate M Saville; Joel F Andrews; Jennifer Clark; Qingming Fang; Jianfeng Li; Rasha Q Al-Rahahleh; Md Ibrahim; Steven McClellan; Mikhail V Makarov; Marie E Migaud; Robert W Sobol
Journal:  Cell Rep       Date:  2021-11-02       Impact factor: 9.423

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.