Piotr Kulig1,2, Przemysław Nowakowski3, Marek Sierzęga4, Radosław Pach4, Oliwia Majewska2, Anna Markiewicz5, Piotr Kołodziejczyk4, Jan Kulig4, Piotr Richter4. 1. Department of Vascular Surgery, American Heart of Poland, Chrzanow, Poland; Kuligos22@interia.pl. 2. Andrzej Frycz Modrzewski Medical Krakow University, Krakow, Poland. 3. Department of Vascular Surgery, American Heart of Poland, Chrzanow, Poland. 4. Department of General, Oncological and Gastrointestinal Surgery, Jagiellonian University Medical College, Krakow, Poland. 5. Department of Ophthalmology and Ocular Oncology, Jagiellonian University Medical College, Krakow, Poland.
Abstract
BACKGROUND: The aim of this study was the analysis of the influence of prognostic factors on short- and long-term outcomes of gastric cancer resection. PATIENTS AND METHODS: A database of 709 patients who had gastric cancer resection between 2007 and 2015 was compiled. RESULTS: Total gastrectomy (TG) and subtotal proximal gastrectomy (SPG) significantly increased the risk of overall complications (p=0.0015 and 0.0173, respectively) and surgical complications (p=0.0141 and 0.0035, respectively). Moreover the resection of an additional organ was an independent prognostic factor of overall complications (p<0.0001), systemic complications (p=0.0503), surgical complications (p<0.0001) and relaparotomy (p=0.0259). T stage (p<0.0001), N stage (p<0.0001), M stage (p<0.0001) and radical resection (p<0.0001) significantly affected 5-year survival rates. CONCLUSION: Early diagnosis and radical resection was crucial in 5-year survival rates. However, the type of gastrectomy and the resection of an additional organ were the most important factors in short-term outcomes of treatment for such patients.
BACKGROUND: The aim of this study was the analysis of the influence of prognostic factors on short- and long-term outcomes of gastric cancer resection. PATIENTS AND METHODS: A database of 709 patients who had gastric cancer resection between 2007 and 2015 was compiled. RESULTS: Total gastrectomy (TG) and subtotal proximal gastrectomy (SPG) significantly increased the risk of overall complications (p=0.0015 and 0.0173, respectively) and surgical complications (p=0.0141 and 0.0035, respectively). Moreover the resection of an additional organ was an independent prognostic factor of overall complications (p<0.0001), systemic complications (p=0.0503), surgical complications (p<0.0001) and relaparotomy (p=0.0259). T stage (p<0.0001), N stage (p<0.0001), M stage (p<0.0001) and radical resection (p<0.0001) significantly affected 5-year survival rates. CONCLUSION: Early diagnosis and radical resection was crucial in 5-year survival rates. However, the type of gastrectomy and the resection of an additional organ were the most important factors in short-term outcomes of treatment for such patients.
Authors: Jin-On Jung; Nerma Crnovrsanin; Naita Maren Wirsik; Henrik Nienhüser; Leila Peters; Felix Popp; André Schulze; Martin Wagner; Beat Peter Müller-Stich; Markus Wolfgang Büchler; Thomas Schmidt Journal: J Cancer Res Clin Oncol Date: 2022-05-26 Impact factor: 4.553