Literature DB >> 34228944

Understanding opioid overdose risk and response preparedness among people who use cocaine and other drugs: Mixed-methods findings from a large, multi-city study.

Jaclyn M W Hughto1,2,3, Lily K Gordon4, Thomas J Stopka5, Patricia Case6, Wilson R Palacios7, Abigail Tapper8, Traci C Green2,4,8.   

Abstract

Background: Fatal overdoses involving cocaine (powdered or crack) and fentanyl have increased nationally and in Massachusetts. It is unclear how overdose risk and preparedness to respond to an overdose differs by patterns of cocaine and opioid use.
Methods: From 2017 to 2019, we conducted a nine-community mixed-methods study of Massachusetts residents who use drugs. Using survey data from 465 participants with past-month cocaine and/or opioid use, we examined global differences (p < 0.05) in overdose risk and response preparedness by patterns of cocaine and opioid use. Qualitative interviews (n = 172) contextualized survey findings.
Results: The majority of the sample (66%) used cocaine and opioids in the past month; 18.9% used opioids alone; 9.2% used cocaine and had no opioid use history; and 6.2% used cocaine and had an opioid use history. Relative to those with a current/past history of opioid use, significantly fewer of those with no opioid use history were aware of fentanyl in the drug supply, carried naloxone, and had received naloxone training. Qualitative interviews documented how people who use cocaine and have no history of opioid use are largely unprepared to recognize and respond to an overdose. Conclusions: Public health efforts are needed to increase fentanyl awareness and overdose prevention preparedness among people primarily using cocaine.

Entities:  

Keywords:  Substance use; cocaine; crack; opioids; overdose

Mesh:

Substances:

Year:  2021        PMID: 34228944      PMCID: PMC9155258          DOI: 10.1080/08897077.2021.1946893

Source DB:  PubMed          Journal:  Subst Abus        ISSN: 0889-7077            Impact factor:   3.984


  44 in total

Review 1.  Understanding polydrug use: review of heroin and cocaine co-use.

Authors:  Francesco Leri; Julie Bruneau; Jane Stewart
Journal:  Addiction       Date:  2003-01       Impact factor: 6.526

2.  Fentanyl and Drug Overdose: Perceptions of Fentanyl Risk, Overdose Risk Behaviors, and Opportunities for Intervention among People who use Opioids in Baltimore, USA.

Authors:  Carl A Latkin; Lauren Dayton; Melissa A Davey-Rothwell; Karin E Tobin
Journal:  Subst Use Misuse       Date:  2019-02-15       Impact factor: 2.164

3.  Latent classes of heroin and cocaine users predict unique HIV/HCV risk factors.

Authors:  P T Harrell; B E Mancha; H Petras; R C Trenz; W W Latimer
Journal:  Drug Alcohol Depend       Date:  2011-10-24       Impact factor: 4.492

4.  Levels and correlates of polydrug use among heroin users and regular amphetamine users.

Authors:  S Darke; W Hall
Journal:  Drug Alcohol Depend       Date:  1995-10       Impact factor: 4.492

5.  Beliefs about the consequences of using benzodiazepines among persons with opioid use disorder.

Authors:  Michael D Stein; Bradley J Anderson; Shannon R Kenney; Genie L Bailey
Journal:  J Subst Abuse Treat       Date:  2017-03-09

6.  Increased Presence of Fentanyl in Cocaine-Involved Fatal Overdoses: Implications for Prevention.

Authors:  Michelle L Nolan; Sindhu Shamasunder; Cody Colon-Berezin; Hillary V Kunins; Denise Paone
Journal:  J Urban Health       Date:  2019-02       Impact factor: 3.671

7.  Understanding disparities in access to naloxone among people who inject drugs in Southeast Michigan using respondent driven sampling.

Authors:  Ai Rene Ong; Sunghee Lee; Erin E Bonar
Journal:  Drug Alcohol Depend       Date:  2019-11-20       Impact factor: 4.492

8.  Distinguishing signs of opioid overdose and indication for naloxone: an evaluation of six overdose training and naloxone distribution programs in the United States.

Authors:  Traci C Green; Robert Heimer; Lauretta E Grau
Journal:  Addiction       Date:  2008-04-16       Impact factor: 6.526

9.  Perspectives on rapid fentanyl test strips as a harm reduction practice among young adults who use drugs: a qualitative study.

Authors:  Jacqueline E Goldman; Katherine M Waye; Kobe A Periera; Maxwell S Krieger; Jesse L Yedinak; Brandon D L Marshall
Journal:  Harm Reduct J       Date:  2019-01-08

10.  Post-overdose interventions triggered by calling 911: Centering the perspectives of people who use drugs (PWUDs).

Authors:  Karla D Wagner; Robert W Harding; Richard Kelley; Brian Labus; Silvia R Verdugo; Elizabeth Copulsky; Jeanette M Bowles; Maria Luisa Mittal; Peter J Davidson
Journal:  PLoS One       Date:  2019-10-17       Impact factor: 3.240

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  1 in total

1.  Association of Methamphetamine and Opioid Use With Nonfatal Overdose in Rural Communities.

Authors:  P Todd Korthuis; Ryan R Cook; Canyon A Foot; Gillian Leichtling; Judith I Tsui; Thomas J Stopka; Judith Leahy; Wiley D Jenkins; Robin Baker; Brian Chan; Heidi M Crane; Hannah L Cooper; Judith Feinberg; William A Zule; Vivian F Go; Angela T Estadt; Robin M Nance; Gordon S Smith; Ryan P Westergaard; Brent Van Ham; Randall Brown; April M Young
Journal:  JAMA Netw Open       Date:  2022-08-01
  1 in total

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