Literature DB >> 34228411

[What are the differences between the various covid-19 vaccines?]

A J M Ligtenberg1, H S Brand1.   

Abstract

The coronavirus pandemic is caused by the SARS-CoV-2. Vaccination appears to offer the way out of this pandemic. Vaccines against this virus make use of the SARS-CoV-2's spike protein, an essential protein on the surface of the virus that it uses to attach itself to the host cells. In viral vector vaccines (AstraZeneca, Sputnik, Johnson & Johnson) the gene for the spike protein is introduced into an adenovirus. Following vaccination, the modified adenovirus will infect cells of the host, which will subsequently start to produce the spike protein, causing an immune response. RNA vaccines (Pfizer, Moderna) only introduce messenger RNA for the spike protein into host cells, which the messenger RNA uses to produce spike protein. Viral vector vaccines and RNA vaccines are not only faster to develop and safer to produce than traditional vaccines, they are also easier to modify to new viruses and virus variants. The latter may be of great importance for future pandemics.

Entities:  

Year:  2021        PMID: 34228411     DOI: 10.5177/ntvt.2021.epub.21038

Source DB:  PubMed          Journal:  Ned Tijdschr Tandheelkd        ISSN: 0028-2200


  2 in total

Review 1.  SARS-CoV-2 vaccine-associated-tinnitus: A review.

Authors:  Syed Hassan Ahmed; Summaiyya Waseem; Taha Gul Shaikh; Nashwa Abdul Qadir; Sarush Ahmed Siddiqui; Irfan Ullah; Abdul Waris; Zohaib Yousaf
Journal:  Ann Med Surg (Lond)       Date:  2022-01-25

2.  Neutralizing antibody titres to SARS-CoV-2 Omicron variant and wild-type virus in those with past infection or vaccinated or boosted with mRNA BNT162b2 or inactivated CoronaVac vaccines.

Authors:  Malik Peiris; Samuel Cheng; Chris Ka Pun Mok; Yonna Leung; Susanna Ng; Karl Chan; Fanny Ko; Karen Yiu; Bosco Lam; Eric Lau; Ken Chan; Leo Luk; John Li; Leo Tsang; Leo Poon; Chunke Chen; David Hui
Journal:  Res Sq       Date:  2022-01-05
  2 in total

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