| Literature DB >> 34226646 |
Maíra Aguiar1,2,3, Joseba Bidaurrazaga Van-Dierdonck4, Javier Mar5,6,7, Nicole Cusimano8, Damián Knopoff8, Vizda Anam8, Nico Stollenwerk8,9.
Abstract
As the COVID-19 pandemic progressed, research on mathematical modeling became imperative and very influential to understand the epidemiological dynamics of disease spreading. The momentary reproduction ratio r(t) of an epidemic is used as a public health guiding tool to evaluate the course of the epidemic, with the evolution of r(t) being the reasoning behind tightening and relaxing control measures over time. Here we investigate critical fluctuations around the epidemiological threshold, resembling new waves, even when the community disease transmission rate [Formula: see text] is not significantly changing. Without loss of generality, we use simple models that can be treated analytically and results are applied to more complex models describing COVID-19 epidemics. Our analysis shows that, rather than the supercritical regime (infectivity larger than a critical value, [Formula: see text]) leading to new exponential growth of infection, the subcritical regime (infectivity smaller than a critical value, [Formula: see text]) with small import is able to explain the dynamic behaviour of COVID-19 spreading after a lockdown lifting, with [Formula: see text] hovering around its threshold value.Entities:
Year: 2021 PMID: 34226646 DOI: 10.1038/s41598-021-93366-7
Source DB: PubMed Journal: Sci Rep ISSN: 2045-2322 Impact factor: 4.379