Literature DB >> 34226111

Utilising an access to care integrated framework to explore the perceptions of hepatitis C treatment of hospital-based interventions among people who use drugs.

Ximena A Levander1, Taylor A Vega2, Andrew Seaman3, P Todd Korthuis4, Honora Englander5.   

Abstract

BACKGROUND: Gaps remain in the hepatitis C virus (HCV) care cascade for people who use drugs (PWUD). Acute medical or surgical illnesses requiring hospitalisation are an opportunity to address addiction, but how inpatient strategies could affect HCV care accessibility for PWUD remains unknown. We explored patient perspectives of hospital-based interventions using an integrated framework of access to HCV care.
METHODS: We conducted a qualitative study of hospitalised adults (n=27) with HCV and addiction admitted to an urban academic medical centre in the United States between June and November 2019. Individual interviews were audio-recorded, transcribed, and dual-coded. We analysed data with coding specific for hospital-based interventions including screening, conducting HCV-related laboratory work-up, starting treatment, connecting with peers, and coordinating outpatient care. We analysed coded data at the semantic level for emergent themes using a framework approach based off an integrated framework of access to HCV care.
RESULTS: The majority of participants primarily used opioids (78%), were white (85%) and men (67%). Participants frequently reported HCV screening during previous hospitalisation with rare inpatient connection to HCV-related services. Participants expressed willingness to discuss HCV treatment candidacy during hospitalisation; however, lack of inpatient conversations led to perception that "nothing could be done" during admission. Participants expressed interest in completing inpatient HCV work-up to "get the ball rollin'" - consolidating care would enhance outpatient service permeability by reducing barriers. Others resisted HCV care coordination, preferring to focus on "immediate" issues including health conditions and addiction treatment. Participants also expressed openness to engaging with peers about HCV, noting shared drug use experience as critical to a peer relationship when discussing HCV.
CONCLUSION: Hospitalised PWUD have varied priorities, necessitating adaptable interventions for addressing HCV. Hospitalisation can be an opportunity to address HCV access to care including identification of treatment eligibility, consolidation of care, and facilitation of HCV-related referrals.
Copyright © 2021. Published by Elsevier B.V.

Entities:  

Keywords:  Hepatitis C virus; Hospital; Qualitative; Substance-related disorders; Theoretical framework

Mesh:

Substances:

Year:  2021        PMID: 34226111      PMCID: PMC8568624          DOI: 10.1016/j.drugpo.2021.103356

Source DB:  PubMed          Journal:  Int J Drug Policy        ISSN: 0955-3959


  66 in total

1.  Hospitals as a 'risk environment': an ethno-epidemiological study of voluntary and involuntary discharge from hospital against medical advice among people who inject drugs.

Authors:  Ryan McNeil; Will Small; Evan Wood; Thomas Kerr
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2.  EASL Recommendations on Treatment of Hepatitis C 2018.

Authors: 
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3.  I don't even want to go to the doctor when I get sick now: Healthcare experiences and discrimination reported by people who use drugs, Arizona 2019.

Authors:  Beth E Meyerson; Danielle M Russell; Michaela Kichler; Tyson Atkin; Graeme Fox; Haley B Coles
Journal:  Int J Drug Policy       Date:  2021-01-15

4.  "Everybody living with a chronic disease is entitled to be cured": Challenges and opportunities in scaling up access to direct-acting antiviral hepatitis C virus treatment among people who inject drugs.

Authors:  Trevor Goodyear; Lianping Ti; Patrizia Carrieri; Will Small; Rod Knight
Journal:  Int J Drug Policy       Date:  2020-05-13

5.  Using framework-based synthesis for conducting reviews of qualitative studies.

Authors:  Mary Dixon-Woods
Journal:  BMC Med       Date:  2011-04-14       Impact factor: 8.775

6.  Conducting a critical interpretive synthesis of the literature on access to healthcare by vulnerable groups.

Authors:  Mary Dixon-Woods; Debbie Cavers; Shona Agarwal; Ellen Annandale; Antony Arthur; Janet Harvey; Ron Hsu; Savita Katbamna; Richard Olsen; Lucy Smith; Richard Riley; Alex J Sutton
Journal:  BMC Med Res Methodol       Date:  2006-07-26       Impact factor: 4.615

Review 7.  The treatment cascade for chronic hepatitis C virus infection in the United States: a systematic review and meta-analysis.

Authors:  Baligh R Yehia; Asher J Schranz; Craig A Umscheid; Vincent Lo Re
Journal:  PLoS One       Date:  2014-07-02       Impact factor: 3.240

8.  Changes to the national strategies, plans and guidelines for the treatment of hepatitis C in people who inject drugs between 2013 and 2016: a cross-sectional survey of 34 European countries.

Authors:  Mojca Maticic; Jerneja Videcnik Zorman; Sergeja Gregorcic; Eberhard Schatz; Jeffrey V Lazarus
Journal:  Harm Reduct J       Date:  2019-05-09

9.  Stigma as a fundamental hindrance to the United States opioid overdose crisis response.

Authors:  Alexander C Tsai; Mathew V Kiang; Michael L Barnett; Leo Beletsky; Katherine M Keyes; Emma E McGinty; Laramie R Smith; Steffanie A Strathdee; Sarah E Wakeman; Atheendar S Venkataramani
Journal:  PLoS Med       Date:  2019-11-26       Impact factor: 11.069

10.  Peer-delivered harm reduction and recovery support services: initial evaluation from a hybrid recovery community drop-in center and syringe exchange program.

Authors:  Robert D Ashford; Brenda Curtis; Austin M Brown
Journal:  Harm Reduct J       Date:  2018-10-22
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