Literature DB >> 3422580

Translocation (3;6)(q21;p21) in acute myeloid leukemia with abnormal thrombopoiesis and basophilia.

C F Hoyle1, P Sherrington, F G Hayhoe.   

Abstract

A case of acute myeloid leukemia (AML) with increased numbers of basophils and abnormal megakaryocytes was shown to have a t(3;6)(q21;p21) in the bone marrow cells. The morphology is described in detail and the case is discussed with reference to t(6;9)(p23;q34) and inv/ins(3)(q21q26) in AML. It is possible that increased numbers of basophils in AML may be associated with a translocation involving 6p21-6p23.

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Year:  1988        PMID: 3422580     DOI: 10.1016/0165-4608(88)90193-8

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  6 in total

1.  Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer.

Authors:  Colleen L Doçi; Tanmayi P Mankame; Alexander Langerman; Kelly R Ostler; Rajani Kanteti; Timothy Best; Kenan Onel; Lucy A Godley; Ravi Salgia; Mark W Lingen
Journal:  Int J Gynecol Pathol       Date:  2012-01       Impact factor: 2.762

2.  Identification and characterization of the human NOL7 gene promoter.

Authors:  Tanmayi P Mankame; Guolin Zhou; Mark W Lingen
Journal:  Gene       Date:  2010-03-03       Impact factor: 3.688

3.  Basophils in acute myeloid leukaemia.

Authors:  C F Hoyle; P D Sherrington; P Fischer; F G Hayhoe
Journal:  J Clin Pathol       Date:  1989-08       Impact factor: 3.411

Review 4.  Acute Basophilic Leukemia: Recent Molecular and Diagnostic Update.

Authors:  Gyanendra Singh
Journal:  Cureus       Date:  2022-06-17

5.  Identification and functional analysis of NOL7 nuclear and nucleolar localization signals.

Authors:  Guolin Zhou; Colleen L Doçi; Mark W Lingen
Journal:  BMC Cell Biol       Date:  2010-09-27       Impact factor: 4.241

6.  Functional analysis of human hematopoietic stem cell gene expression using zebrafish.

Authors:  Craig E Eckfeldt; Eric M Mendenhall; Catherine M Flynn; Tzu-Fei Wang; Michael A Pickart; Suzanne M Grindle; Stephen C Ekker; Catherine M Verfaillie
Journal:  PLoS Biol       Date:  2005-07-05       Impact factor: 8.029

  6 in total

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