Literature DB >> 34225494

An Open-Source Toolkit To Expand Bioinformatics Training in Infectious Diseases.

Alexander S F Berry1,2, Camila Farias Amorim1, Corbett L Berry1, Camille M Syrett3, Elise D English1, Daniel P Beiting1.   

Abstract

As access to high-throughput sequencing technology has increased, the bottleneck in biomedical research has shifted from data generation to data analysis. Here, we describe a modular and extensible framework for didactic instruction in bioinformatics using publicly available RNA sequencing data sets from infectious disease studies, with a focus on host-parasite interactions. We highlight lessons learned from adapting this course for virtual learners during the coronavirus disease 2019 (COVID-19) pandemic.

Entities:  

Keywords:  bioinformatics; education; genomics; infectious disease; transcription

Year:  2021        PMID: 34225494     DOI: 10.1128/mBio.01214-21

Source DB:  PubMed          Journal:  mBio            Impact factor:   7.867


  3 in total

1.  Balanced control of thermogenesis by nuclear receptor corepressors in brown adipose tissue.

Authors:  Hannah J Richter; Amy K Hauck; Kirill Batmanov; Shin-Ichi Inoue; Bethany N So; Mindy Kim; Matthew J Emmett; Ronald N Cohen; Mitchell A Lazar
Journal:  Proc Natl Acad Sci U S A       Date:  2022-08-08       Impact factor: 12.779

2.  CLIP-Seq to identify targets and interactions of RNA binding proteins and RNA modifying enzymes.

Authors:  Julian Stoute; Kathy Fange Liu
Journal:  Methods Enzymol       Date:  2021-08-23       Impact factor: 1.682

3.  Impact of secondary TCR engagement on the heterogeneity of pathogen-specific CD8+ T cell response during acute and chronic toxoplasmosis.

Authors:  Lindsey A Shallberg; Anthony T Phan; David A Christian; Joseph A Perry; Breanne E Haskins; Daniel P Beiting; Tajie H Harris; Anita A Koshy; Christopher A Hunter
Journal:  PLoS Pathog       Date:  2022-06-21       Impact factor: 7.464

  3 in total

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