Literature DB >> 3422215

Loss of der(3) in renal carcinoma cells of a patient with constitutional t(3;12).

G Kovacs1, E Hoene.   

Abstract

Cytogenetic studies were performed on peripheral lymphocytes, normal kidney cells, and tumor cells of a patient with renal cell carcinoma. Chromosome analysis of normal somatic cells revealed a constitutional t(3;12)(q13.2;q24.1) and a genomic instability involving the derivative chromosome 12. On the other hand, tumor cells were characterized by loss of der(3), supporting the hypothesis that loss of a specific 3p segment is associated with the development of renal cancer.

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Year:  1988        PMID： 3422215     DOI： 10.1007/BF00278186

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  11 in total

1.  Epidemiology of chromosome abnormalities in man.

Authors:  P A Jacobs
Journal:  Am J Epidemiol       Date:  1977-03       Impact factor: 4.897

2.  A case of rhabdomyosarcoma of the bladder with a (2;5) chromosomal translocation in peripheral lymphocytes.

Authors:  M Moriyama; T Shuin; Y Kubota; Y Satomi; Y Sugio; Y Kuroki
Journal:  Cancer Genet Cytogenet       Date:  1986-06

3.  Constitutional chromosomal aberration, t(4;12) (q23;p11), in a patient with Ph1 positive chronic myelocytic leukemia.

Authors:  G Gahrton; K Friberg; L Zech
Journal:  Hereditas       Date:  1978       Impact factor: 3.271

4.  Familial renal cell carcinoma with a 3;11 chromosome translocation limited to tumor cells.

Authors:  S Pathak; L C Strong; R E Ferrell; A Trindade
Journal:  Science       Date:  1982-09-03       Impact factor: 47.728

5.  Hereditary renal-cell carcinoma associated with a chromosomal translocation.

Authors:  A J Cohen; F P Li; S Berg; D J Marchetto; S Tsai; S C Jacobs; R S Brown
Journal:  N Engl J Med       Date:  1979-09-13       Impact factor: 91.245

6.  In vitro hyperdiploidy in a family with nasopharyngeal cancer.

Authors:  B S Danes
Journal:  Cancer Genet Cytogenet       Date:  1986-03-15

7.  The clonal evolution of tumor cell populations.

Authors:  P C Nowell
Journal:  Science       Date:  1976-10-01       Impact factor: 47.728

8.  Chromosomes in kidney, ureter, and bladder cancer.

Authors:  C S Berger; A A Sandberg; I A Todd; R D Pennington; F S Haddad; B K Hecht; F Hecht
Journal:  Cancer Genet Cytogenet       Date:  1986-09

9.  Cytogenetic studies of tumor tissue from patients with nonfamilial renal cell carcinoma.

Authors:  M A Yoshida; K Ohyashiki; H Ochi; Z Gibas; J E Pontes; G R Prout; R Huben; A A Sandberg
Journal:  Cancer Res       Date:  1986-04       Impact factor: 12.701

10.  Numerical and structural chromosome aberrations in cultured lymphocytes and cutaneous fibroblasts of patients with multiple adenomas of the colorectum.

Authors:  E J Gardner; S W Rogers; S Woodward
Journal:  Cancer       Date:  1982-04-01       Impact factor: 6.860
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  3 in total

1.  An alternative route for multistep tumorigenesis in a novel case of hereditary renal cell cancer and a t(2;3)(q35;q21) chromosome translocation.

Authors:  D Bodmer; M J Eleveld; M J Ligtenberg; M A Weterman; B A Janssen; D F Smeets; P E de Wit; A van den Berg; E van den Berg; M I Koolen; A Geurts van Kessel
Journal:  Am J Hum Genet       Date:  1998-06       Impact factor: 11.025

2.  Association of a novel constitutional translocation t(1q;3q) with familial renal cell carcinoma.

Authors:  H Kanayama ; W O Lui; M Takahashi; T Naroda; D Kedra; F K Wong; Y Kuroki; Y Nakahori; C Larsson; S Kagawa; B T Teh
Journal:  J Med Genet       Date:  2001-03       Impact factor: 6.318

3.  Familial renal cell carcinoma: clinical and molecular genetic aspects.

Authors:  E R Maher; J R Yates
Journal:  Br J Cancer       Date:  1991-02       Impact factor: 7.640
  3 in total

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