Background: Periodontal disease continues to be prevalent globally, but little clinical research has been undertaken to evaluate the long-term benefits of a daily oral hygiene regimen on progression of gingivitis/early periodontitis. The objective of this study was to evaluate the effects of an oral hygiene regimen (OHR) on the periodontal health of adults in good general health with established gingivitis and early periodontitis over 24 months. Methods: A randomized controlled trial was conducted in adults with established gingivitis, with isolated sites of probing pocket depth >4 mm. Study participants were randomized to the OHR (bioavailable stannous fluoride dentifrice, oscillating-rotating electric toothbrush, cetylpyridinium chloride rinse, and floss; P&G) or usual care products (sodium fluoride dentifrice and manual toothbrush; P&G) groups. At baseline and every 6 months, gingivitis and periodontal measures were assessed and a prophylaxis was conducted. The primary outcome was Gingival Bleeding Index-Bleeding Sites (GBI-BS). Analyses used ANCOVA at 5% significance levels. Results: A total of 107 individuals were enrolled; 87 completed the study. Mean GBI-BS, Modified Gingival Index, and Probing Pocket Depth (PPD) scores were significantly lower at each visit for the OHR versus usual care group by 28% to 39%, 12% to 18%, and 6% to 13%, respectively (p≤ 0.0009). The magnitude of reduction in median number of ≥2 mm PPD loss events for OHR versus the usual care group at 24 months was 74%. Conclusion: Long-term use of the OHR produced significant periodontal health improvements versus the usual care products.
Background: Periodontal disease continues to be prevalent globally, but little clinical research has been undertaken to evaluate the long-term benefits of a daily oral hygiene regimen on progression of gingivitis/early periodontitis. The objective of this study was to evaluate the effects of an oral hygiene regimen (OHR) on the periodontal health of adults in good general health with established gingivitis and early periodontitis over 24 months. Methods: A randomized controlled trial was conducted in adults with established gingivitis, with isolated sites of probing pocket depth >4 mm. Study participants were randomized to the OHR (bioavailable stannous fluoride dentifrice, oscillating-rotating electric toothbrush, cetylpyridinium chloride rinse, and floss; P&G) or usual care products (sodium fluoride dentifrice and manual toothbrush; P&G) groups. At baseline and every 6 months, gingivitis and periodontal measures were assessed and a prophylaxis was conducted. The primary outcome was Gingival Bleeding Index-Bleeding Sites (GBI-BS). Analyses used ANCOVA at 5% significance levels. Results: A total of 107 individuals were enrolled; 87 completed the study. Mean GBI-BS, Modified Gingival Index, and Probing Pocket Depth (PPD) scores were significantly lower at each visit for the OHR versus usual care group by 28% to 39%, 12% to 18%, and 6% to 13%, respectively (p≤ 0.0009). The magnitude of reduction in median number of ≥2 mm PPD loss events for OHR versus the usual care group at 24 months was 74%. Conclusion: Long-term use of the OHR produced significant periodontal health improvements versus the usual care products.
Authors: Søren Jepsen; Juan Blanco; Wolfgang Buchalla; Joana C Carvalho; Thomas Dietrich; Christof Dörfer; Kenneth A Eaton; Elena Figuero; Jo E Frencken; Filippo Graziani; Susan M Higham; Thomas Kocher; Marisa Maltz; Alberto Ortiz-Vigon; Julian Schmoeckel; Anton Sculean; Livia M A Tenuta; Monique H van der Veen; Vita Machiulskiene Journal: J Clin Periodontol Date: 2017-03 Impact factor: 8.728
Authors: Maurizio S Tonetti; Peter Eickholz; Bruno G Loos; Panos Papapanou; Ubele van der Velden; Gary Armitage; Philippe Bouchard; Renate Deinzer; Thomas Dietrich; Frances Hughes; Thomas Kocher; Niklaus P Lang; Rodrigo Lopez; Ian Needleman; Tim Newton; Luigi Nibali; Bernadette Pretzl; Christoph Ramseier; Ignacio Sanz-Sanchez; Ulrich Schlagenhauf; Jean E Suvan Journal: J Clin Periodontol Date: 2015-04 Impact factor: 8.728
Authors: Aaron Biesbrock; Patrick M A Corby; Robert Bartizek; Andrea L Corby; Mania Coelho; Simone Costa; Walter A G Bretz; Walter A Bretz Journal: J Periodontol Date: 2006-08 Impact factor: 6.993
Authors: Georgios A Kotsakis; Qinshu Lian; Andreas L Ioannou; Bryan S Michalowicz; Mike T John; Haitao Chu Journal: J Periodontol Date: 2018-05 Impact factor: 6.993
Authors: Marc Schätzle; Harald Löe; Niklaus P Lang; Walter Bürgin; Age Anerud; Hans Boysen Journal: J Clin Periodontol Date: 2004-12 Impact factor: 8.728
Authors: Marc Schätzle; Harald Löe; Walter Bürgin; Age Anerud; Hans Boysen; Niklaus P Lang Journal: J Clin Periodontol Date: 2003-10 Impact factor: 8.728