Literature DB >> 3422048

Cytogenetics of 12 cases of renal adenocarcinoma.

B de Jong1, J W Oosterhuis, V J Idenburg, S M Castedo, A Dam, H J Mensink.   

Abstract

The cytogenetics of 12 cases of renal adenocarcinoma are presented. Clonal abnormalities were found in nine patients. Worth mentioning are abnormalities of the X chromosome (1 X) and the chromosomes #1(3 X), #3(3 X), #7(4 X), #8(4 X), and #14(2 X). From our data and data from the literature it appeared that the chromosomal regions 3p11-p21, 1q21, 14q22, and Xp11 are important for the oncogenesis of renal cell carcinoma as well as increased dosage of chromosome #7 and loss or abnormalities of chromosomes #8 and #14.

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Year:  1988        PMID： 3422048     DOI： 10.1016/0165-4608(88)90092-1

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  8 in total

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